Esophageal diverticula and cancer

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
F A M HerbellaMarco G Patti

Abstract

Esophageal diverticula are rare. The association of cancer and diverticula has been described. Some authors adopt a conservative non-surgical approach in selected patients with diverticula whereas others treat the symptoms by diverticulopexy or myotomy only, leaving the diverticulum in situ. However, the risk of malignant degeneration should be may be taken in account if the diverticulum is not resected. The correct evaluation of the possible risk factors for malignancy may help in the decision making process. We performed a literature review of esophageal diverticula and cancer. The incidence of cancer in a diverticulum is 0.3-7, 1.8, and 0.6% for pharyngoesophageal, midesophageal, and epiphrenic diverticula, respectively. Symptoms may mimic those of the diverticulum or underlying motor disorder. Progressive dysphagia, unintentional weight loss, the presence of blood in the regurgitated material, regurgitation of peaces of the tumor, odynophagia, melena, hemathemesis, and hemoptysis are key symptoms. Risk factors for malignancy are old age, male gender, long-standing history, and larger diverticula. A carcinoma may develop in treated diverticula, even after resection. Outcomes are usually quoted as dismal because of a delayed ...Continue Reading

References

Aug 3, 1979·JAMA : the Journal of the American Medical Association·R A Cooper
Mar 1, 1977·AJR. American Journal of Roentgenology·Y Ben-MenachemB L Harberg
Feb 1, 1976·The Journal of Laryngology and Otology·I S Mackay
May 1, 1976·The British Journal of Surgery·E M Nanson
Oct 1, 1990·The Journal of Laryngology and Otology·M J Burton, W S Lund
Feb 1, 1989·Journal of Clinical Gastroenterology·B M JensenK Andersen
Jul 1, 1989·The Journal of Laryngology and Otology·D J Stevens
Jul 1, 1987·The British Journal of Surgery·D A Bowdler, P M Stell
May 1, 1987·Head & Neck Surgery·R P ZitschW A Maddox
Jun 1, 1987·European Journal of Cancer & Clinical Oncology·T J McMillanG G Steel
Mar 1, 1985·The Journal of Laryngology and Otology·M E Baraka, S A Sadek
Oct 1, 1985·The Journal of Urology·D J Rivard, S S Waisman
Jan 1, 1967·Archives of Surgery·M L Som, M Deitel
Jul 1, 1968·The Annals of Thoracic Surgery·R C Thomas
Aug 1, 1971·Southern Medical Journal·M S Shin
Nov 1, 1969·The Journal of Laryngology and Otology·H B Juby
Nov 1, 1970·American Journal of Surgery·B M DillowR D Sellers
Jan 1, 1982·Gastrointestinal Radiology·J A SaldanaG A Bannayan
Jun 1, 1995·Chest·D J SugarbakerM J Liptay
May 1, 1994·American Journal of Otolaryngology·M M KernerR A Mickel
Sep 1, 1995·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·F A Aleem, M Predanic
Feb 1, 1996·Journal of the American Academy of Dermatology·M H LowittG F Kao
Feb 1, 1997·Endoscopy·B HerterJ R Siewert
Dec 9, 1998·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·G CastrucciA Picciocchi
Jan 8, 1999·World Journal of Surgery·P H Jordan, B M Kinner
Dec 1, 1999·The Annals of Otology, Rhinology, and Laryngology·P J BradleyM S Quraishi
Feb 2, 2000·The Annals of Thoracic Surgery·E Avisar, J D Luketich
May 15, 2001·The British Journal of Surgery·M L ThomasG J Maddern
Mar 8, 2002·Annals of Surgery·Dhiren NehraCedric G Bremner
May 31, 2003·Gastrointestinal Endoscopy·Hidekazu HondaMakoto Otsuki
Aug 1, 1954·American Journal of Surgery·J M BEARDSLEY
Oct 1, 1956·A.M.A. Archives of Internal Medicine·F S CROSS, E B KAY
Dec 1, 1958·Thorax·I M MORRISON
Aug 1, 1961·Annals of Surgery·J H GARLOCK, R RICHTER
Mar 1, 1963·The British Journal of Radiology·M J TURNER
May 1, 1951·American Journal of Surgery·R M HOYNE, J C T ROGERS
Jul 1, 1952·Cancer·W K BULLOCK, E N SNYDER
May 14, 2004·Digestive Diseases and Sciences·Fernando A M HerbellaJose C Del Grande
Jul 9, 2004·Annals of the Royal College of Surgeons of England·M A Siddiq, S Sood
Apr 1, 1950·The British Journal of Surgery·T DUNHILL

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Citations

Sep 3, 2011·Langenbeck's Archives of Surgery·Fernando A M Herbella, Marco G Patti
Mar 18, 2015·Asian Journal of Surgery·Sze Li SiowMark Hardin
Aug 29, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Carolina Morales MinoviPhilipp Dost
Jul 15, 2015·Arab Journal of Gastroenterology : the Official Publication of the Pan-Arab Association of Gastroenterology·Chia-Ming Chang, Hsien-Hao Huang
Jul 7, 2015·Polski przeglad chirurgiczny·Adam BobkiewiczMichał Drews
Jan 23, 2015·World Journal of Surgery·P Marco FisichellaAdrian Dobrowolsky
Jan 23, 2015·World Journal of Surgery·Fernando A M Herbella, Marco G Patti
Sep 4, 2012·International Journal of Surgery Case Reports·Akiyuki WakitaJun-Ichi Ogawa
Jan 20, 2018·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·C A Gutschow, H Schmidt
Feb 13, 2015·Clinical Endoscopy·Ah Ran ChoiHyojin Park
May 31, 2019·Clinical Oral Investigations·Jorge PerdigãoMa Victoria Fuentes
Apr 2, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·David J WeilandSunil P Verma
Apr 22, 2020·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Lavinia A BarbieriRiccardo Rosati
Nov 30, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Ian HolmesPriya Kathpalia
Nov 26, 2016·Case Reports in Gastrointestinal Medicine·Muhammad ChowdhryAlexandros Charalabopoulos
Jan 15, 2020·Surgical Case Reports·Kohei SaishoYoshito Akagi
Feb 2, 2021·Risk Management and Healthcare Policy·Ping-Xin QiXu-Hui Gao
Jun 5, 2020·Cirugía española·Olga Luengo BallesterEmilio García Blázquez
Oct 15, 2021·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Raquel Muñoz GonzálezCecilio Santander

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