Esophageal Magnetic Sphincter Augmentation as a Novel Approach to Post-bariatric Surgery Gastroesophageal Reflux Disease

Obesity Surgery
John P KuckelmanMatthew J Martin

Abstract

We sought to evaluate the safety and effectiveness of magnetic sphincter augmentation (MSA) in patients with GERD after bariatric surgery. Pre- and post-operative GERD quality of life (G-QOL) surveys were conducted. Standard indications (SI) group or the post-bariatric group (PB) created. Outcomes were compared between groups. Twenty-eight patients analyzed with no losses to follow-up. All patients had preoperative testing confirming normal motility and presence of GERD. No patients were lost to follow-up. The PB group (N = 10) were mostly prior sleeve gastrectomies (N = 8) with two previous gastric bypasses. PB patients required larger MSA device size (16 beads) compared to the SI group (14 beads, p < 0.001). Outcomes were no different with percent improvement between pre- and post-operative G-QOL survey scores with 70% improvement for PB and 84% for SI (p = 0.13). Medication cessation was possible in 90% for PB versus 94% for SI (p = 0.99). Rates of post-operative dysphagia were similar between the two groups. Although larger prospective randomized studies are needed, there is an exciting potential for the role of MSA, providing surgeons a new and much needed tool in their armamentarium against refractory or de novo GERD afte...Continue Reading

References

Oct 26, 2005·The Annals of Thoracic Surgery·Raymond H ChenRaphael Bueno
Apr 28, 2012·Surgical Endoscopy·John C LiphamWillem Bemelman
Jun 6, 2012·Clinics·Nilton T KawaharaLuiz Francisco Poli-de-Figueiredo
Aug 8, 2012·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Emanuele SoricelliNicola Basso
Mar 13, 2014·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·J C LiphamT R Demeester
Mar 29, 2014·Canadian Journal of Surgery. Journal Canadien De Chirurgie·Mustafa El-HadiShahzeer Karmali
Sep 10, 2014·Best Practice & Research. Clinical Gastroenterology·Jan Tack, Eveline Deloose
May 13, 2015·The Surgical Clinics of North America·Maria S Altieri, Aurora D Pryor
Jul 15, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kenneth DesartKfir Ben-David
Sep 4, 2015·Surgical Endoscopy·Radu PescarusKevin M Reavis
Oct 3, 2015·Obesity Surgery·John MelissasMirto Foletto
Oct 6, 2015·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Greta SainoRobert A Ganz
Jan 23, 2016·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·LéShon HendricksRaul Rosenthal
Jun 19, 2016·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Abdelkader HawasliMoayad Tarboush
Aug 25, 2016·Surgical Endoscopy·Kais A RonaJohn C Lipham

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Citations

Jun 24, 2020·Surgical Endoscopy·Omar BellorinCheguevara Afaneh
Dec 5, 2020·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Benjamin ClappBrian Davis
Mar 25, 2021·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Benjamin Clapp

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