PMID: 6985885Jan 1, 1980Paper

Essential and nonessential cooperative signals in lymphocyte triggering in solid cultures

International Archives of Allergy and Applied Immunology
E Kondracki

Abstract

The kinetics of lymphocyte stimulation by mitogens in solid cultures were used to study the role of cell interactions in these responses. An absolute requirement for cell interactions, possibly through soluble mediators, was found in lymphocyte responses to calcium ionophore A23187, phytohemagglutinin HA17 and tetradecanoylphorbol acetate. Accessory leukocytes were adherent to plastic surfaces and did form E rosettes. Autologous erythrocytes were also capable of providing essential cooperative signals. 2-Mercaptoethanol, in contrast, only provided nonessential cooperative signals for lymphocyte stimulation in solid cultures.

Citations

Jun 1, 1981·Veterinary Immunology and Immunopathology·G A SplitterW R Usinger
Jan 1, 1982·Immunological Communications·M E DefreitasN E Bianco

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

© 2021 Meta ULC. All rights reserved