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Essential cell-autonomous role for interferon (IFN) regulatory factor 1 in IFN-γ-mediated inhibition of norovirus replication in macrophages

Journal of Virology

Sep 14, 2012

Nicole S MaloneyHerbert W Virgin

Abstract

Noroviruses (NVs) cause the majority of cases of epidemic nonbacterial gastroenteritis worldwide and contribute to endemic enteric disease. However, the molecular mechanisms responsible for immune control of their replication are not completely understood. Here we report that the transc...read more

Mentioned in this Paper

IRF7 gene
Microarray Analysis
Mice, Knockout
Metabolic Inhibition
Interferon Type II
Interferons
Stat1 protein, mouse
IRF1 protein, human
Specimen Type - Macrophages
Macrophage
Paper Details
References
  • References41
  • Citations13
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  • References41
  • Citations13
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Essential cell-autonomous role for interferon (IFN) regulatory factor 1 in IFN-γ-mediated inhibition of norovirus replication in macrophages

Journal of Virology

Sep 14, 2012

Nicole S MaloneyHerbert W Virgin

PMID: 22973039

DOI: 10.1128/jvi.01564-12

Abstract

Noroviruses (NVs) cause the majority of cases of epidemic nonbacterial gastroenteritis worldwide and contribute to endemic enteric disease. However, the molecular mechanisms responsible for immune control of their replication are not completely understood. Here we report that the transc...read more

Mentioned in this Paper

IRF7 gene
Microarray Analysis
Mice, Knockout
Metabolic Inhibition
Interferon Type II
Interferons
Stat1 protein, mouse
IRF1 protein, human
Specimen Type - Macrophages
Macrophage

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References41
  • Citations13
12345
  • References41
  • Citations13
12
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