PMID: 2114321Jul 2, 1990Paper

Essential role of ferrous iron in cyanide-resistant respiration in Hansenula anomala

FEBS Letters
Nobuko MinagawaA Yoshimoto

Abstract

Antimycin A-dependent induction of cyanide-resistant respiration in Hansenula anomala was completely blocked by o-phenanthroline, alpha,alpha'-dipyridyl, or 8-hydroxyquinoline. Pulse-labeling of the cells with [35S]methionine in the presence of both antimycin A and o-phenanthroline indicated that the 36-kDa protein previously reported to be involved in cyanide-resistant respiration [(1989) J. Biochem. 105, 864-866] was formed in mitochondria even under these conditions. The addition of Fe2+, but not Fe3+, ions to these cells in the presence of cycloheximide resulted in the rapid expression of cyanide-resistant respiration activity. These results suggest that in the presence of both antimycin A and o-phenanthroline an inactive form of the 36-kDa protein was formed and Fe2+ ions converted it to the active form. It is also likely that Fe2+ ions are involved in the reaction mechanism of cyanide-resistant respiration.

References

Mar 1, 1989·Molecular and Cellular Biology·A M LambowitzL McIntosh
May 1, 1987·Journal of Biochemistry·N Minagawa, A Yoshimoto
Dec 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·T E Elthon, L McIntosh

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Citations

Aug 1, 1995·Journal of Bioenergetics and Biomembranes·A L MooreJ N Siedow
Aug 1, 1995·Journal of Bioenergetics and Biomembranes·D A Day, J T Wiskich
Sep 22, 2009·The Journal of Biological Chemistry·Amandine MaréchalPeter R Rich
Sep 25, 2003·Annual Review of Plant Biology·Deborah A Berthold, Pål Stenmark
Feb 25, 2003·Bioscience, Biotechnology, and Biochemistry·Nobuko MinagawaAkio Yoshimoto
May 4, 2013·Annual Review of Plant Biology·Anthony L MooreKikukatsu Ito
Feb 5, 2008·Biochimica Et Biophysica Acta·Anthony L MoorePeter Heathcote
Feb 12, 2004·Biochimica Et Biophysica Acta·Charles Affourtit, Anthony L Moore
Dec 7, 2000·Biochimica Et Biophysica Acta·D A BertholdP Nordlund
Jun 6, 2009·Physiologia Plantarum·Allison E McDonald
Dec 23, 2009·Biochimica Et Biophysica Acta·Edward A BerryNobuko Minagawa
Apr 12, 2003·FEMS Yeast Research·Alexandra VeigaMaria C Loureiro-Dias
Sep 7, 2002·The Journal of Biological Chemistry·Deborah A BertholdPär Nordlund
May 4, 1999·FEBS Letters·M E Andersson, P Nordlund
Mar 14, 2003·FEBS Letters·Coichi NiheiKiyoshi Kita
Sep 17, 2008·Biochemical Society Transactions·Anthony L Moore, Mary S Albury
Mar 10, 2015·Biochemistry. Biokhimii︠a︡·A G RogovR A Zvyagilskaya
Mar 14, 2001·Biochimica Et Biophysica Acta·T Joseph-HorneP M Wood
Jun 3, 2021·Membranes·Deborah M BoesDuncan G G McMillan

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