Essential Tremor - A Cerebellar Driven Disorder?

Neuroscience
Mohamed Fasil IbrahimRuth M Empson

Abstract

Abnormal tremors are the most common of all movement disorders. In this review we focus on the role of the cerebellum in Essential Tremor, a highly debilitating but poorly treated movement disorder. We propose a variety of mechanisms driving abnormal burst firing of deep cerebellar nuclei neurons as a key initiator of tremorgenesis in Essential Tremor. Targetting these mechanisms may generate more effective treatments for Essential Tremor.

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Citations

Apr 25, 2021·Neuroscience·Soichi NagaoMichisuke Yuzaki

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