Establishing reference values for mean notch depth index, pulsatility index and resistance index in the uterine artery at 16-23 weeks' gestation

The Journal of Obstetrics and Gynaecology Research
Kayo TakahashiMitsuaki Suzuki

Abstract

Our aim was to determine the reference values of indices of impedance to flow in uterine arteries at 16-23 weeks, and to evaluate the effects of these indices for predicting early-onset pre-eclampsia (EO-PE), which was defined as PE with onset at <32 weeks. During 2004 to 2008, 1536 women with a singleton pregnancy were recruited into a prospective cohort study at 16-23 weeks. The mean notch depth index (mNDI), mean pulsatility index (mPI) and mean resistance index (mRI) were calculated. Early-onset pre-eclampsia occurred in 16 (1.0%). The 80th, 90th, 95th and 97.5th percentiles of the mNDI at 16-23 weeks were determined. Normal reference ranges of the mPI and mRI were constructed, and individual standard deviation scores (SDS) of the mPI and mRI were calculated. The area under the receiver-operating characteristics curves (AROC) of the mNDI, mPI, mRI and bilateral notching (BN) for predicting EO-PE were 0.807, 0.809, 0.782 and 0.798, respectively. For predicting EO-PE, a mNDI of the 90th percentile, mPI-SDS of 1.383, mRI-SDS of 0.975 and BN yielded sensitivities (specificities) of 0.688 (0.886), 0.750 (0.889), 0.813 (0.809) and 0.750 (0.845) with positive likelihood ratios and 95% confidence intervals of 6.0 (4.2-8.6), 6.8 (4....Continue Reading

References

Mar 1, 1996·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·K HarringtonS Campbell
Nov 20, 1998·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·W KurdiK Harrington
Feb 19, 2000·The Journal of Obstetrics and Gynaecology Research·A YamauchiI Sato
Dec 16, 2000·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A OhkuchiM Tateno
Feb 13, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M W AardemaJ G Aarnoudse
Feb 15, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A T PapageorghiouUNKNOWN Fetal Medicine Foundation Second Trimester Screening Group
Aug 16, 2005·American Journal of Obstetrics and Gynecology·Christina K H YuUNKNOWN Fetal Medicine Foundation Second Trimester Screening Group
Mar 12, 2008·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Jeltsje S CnossenKhalid S Khan

❮ Previous
Next ❯

Citations

Aug 16, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Chikako HirashimaMitsuaki Suzuki
Jan 30, 2015·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Ibrahim PolatCemal Ark
Sep 13, 2015·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Shiho NagayamaShigeki Matsubara
Jun 4, 2014·The Journal of Obstetrics and Gynaecology Research·Takako TaguchiNobuaki Mitsuda
Dec 8, 2016·Acta Obstetricia Et Gynecologica Scandinavica·Solhild StridsklevEszter Vanky
Mar 7, 2014·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Chikako HirashimaMitsuaki Suzuki
Apr 24, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ellen E GillisJennifer M Sasser
Oct 6, 2017·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Chikako HirashimaShigeki Matsubara

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
Aris T PapageorghiouFetal Medicine Foundation Second Trimester Screening Group
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
Kevin HarringtonS Campbell
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
Wesam KurdiKevin Harrington
© 2021 Meta ULC. All rights reserved