Establishing the diagnosis of Libman-Sacks endocarditis in systemic lupus erythematosus.

Journal of General Internal Medicine
Geraldine E Ménard

Abstract

A 43-year-old female with systemic lupus erythematosus (SLE) was admitted with fever and shortness of breath 1 month after aortic valve replacement. A diagnostic workup including chemistries, complete blood count, blood cultures, chest x-ray, and 2-D echocardiogram was performed to determine the etiology of her symptoms and differentiate between acute bacterial endocarditis and Libman-Sacks endocarditis. By utilizing Duke's criteria, antiphospholipid antibodies, and serial echocardiography, we were able to make a diagnosis of Libman-Sacks endocarditis. The patient was successfully treated for Libman-Sacks endocarditis and recovered uneventfully. This case highlights the challenges of making the correct diagnosis when 2 disease processes present with similar findings.

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Citations

Mar 5, 2013·Current Rheumatology Reports·Stéphane ZuilyDenis Wahl
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Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.