Establishment of a Novel Scoring System for Colon Capsule Endoscopy to Assess the Severity of Ulcerative Colitis-Capsule Scoring of Ulcerative Colitis

Inflammatory Bowel Diseases
Naoki HosoeHaruhiko Ogata

Abstract

The usefulness of second-generation colon capsule endoscopy (CCE-2) for ulcerative colitis (UC) has not been fully demonstrated. This study aimed to develop an endoscopic severity score of UC for CCE-2. Patients diagnosed with UC were enrolled prospectively and underwent colonoscopy and CCE-2 on the same day. The collected CCE-2 videos were adopted for the development of the score. These videos were scored by 4 blinded inflammatory bowel disease experts. The items validated with the Ulcerative Colitis Endoscopic Index of Severity (UCEIS) were used as the candidate items, some of which were automatically assessed using the workstation. Each item was divided into proximal and distal parts at the splenic flexure and then individually assessed. The image readers simultaneously evaluated the inflammation severity using the visual analog scale (VAS). The descriptors that contribute to this scale were evaluated, and a model to predict the VAS was constructed. The UCEIS was scored by other endoscopists using colonoscopy videos. The correlation coefficients with fecal calprotectin, blood tests, and Lichtiger index were calculated. The final scoring system was fixed as "vascular pattern sum (proximal + distal) + bleeding sum + erosions a...Continue Reading

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Citations

Jul 7, 2020·Intestinal research·Ida Hilmi, Taku Kobayashi
Aug 18, 2020·Journal of Gastroenterology and Hepatology·Mao MatsubayashiToshifumi Hibi
Jun 17, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Naoki HosoeTakanori Kanai
Jan 10, 2020·Clinical Endoscopy·Naoki HosoeHaruhiko Ogata
Mar 16, 2021·Therapeutic Advances in Gastrointestinal Endoscopy·Benjamin Gutierrez BeckerMarco Prunotto
Jun 3, 2021·Journal of Clinical Medicine·Trevor TabonePierre Ellul

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