Establishment of an Italian chronic migraine database: a multicenter pilot study

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Piero BarbantiN Vanacore

Abstract

To optimize chronic migraine (CM) ascertainment and phenotype definition, provide adequate clinical management and health care procedures, and rationalize economic resources allocation, we performed an exploratory multicenter pilot study aimed at establishing a CM database, the first step for developing a future Italian CM registry. We enrolled 63 consecutive CM patients in four tertiary headache centers screened with face-to-face interviews using an ad hoc dedicated semi-structured questionnaire gathering detailed information on life-style, behavioral and socio-demographic factors, comorbidities, and migraine features before and after chronicization and healthcare resource use. Our pilot study provided useful insights revealing that CM patients (1) presented in most cases symptoms of peripheral trigeminal sensitization, a relatively unexpected feature which could be useful to unravel different CM endophenotypes and to predict trigeminal-targeted treatments' responsiveness; (2) had been frequently admitted to emergency departments; (3) had undergone, sometime repeatedly, unnecessary or inappropriate investigations; (4) got rarely illness benefit exemption or disability allowance only. We deem that the expansion of the database-...Continue Reading

References

Feb 15, 2012·Nature Reviews. Neurology·Hans-Christoph DienerStephen D Silberstein
Jun 19, 2013·Cephalalgia : an International Journal of Headache·UNKNOWN Headache Classification Committee of the International Headache Society (IHS)
Jul 6, 2014·Headache·Stephen D SilbersteinDavid W Dodick
May 28, 2015·The New England Journal of Medicine·J Larry Jameson, Dan L Longo
May 21, 2017·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Piero BarbantiPatrizia Ferroni
Oct 17, 2017·Journal of Pain Research·Piero Barbanti, Patrizia Ferroni

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Citations

Sep 1, 2019·The Journal of Headache and Pain·Elio Clemente AgostoniUNKNOWN Italian chronic migraine group
Apr 12, 2019·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Piero BarbantiRaffaele Palmirotta

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