PMID: 4288399Dec 2, 1966Paper

Establishment of four functional, clonal strains of animal cells in culture

Science
Y YasamuraG Sato

Abstract

The single-cell plating technique was used to develop four clonal cell lines that perform organ-specific functions after being serially cultured for prolonged periods. These strains include steroid-secreting Leydig cells, melanomacells that form pigment, and two strains from a hormone-secreting rat pituitary tumor. One of the cell lines from the pituitary tumor secretes growt hormone, while another line derived from the same tumor secretes a substance similar to adrenocorticotropic hormone.

References

Jul 15, 1962·Proceedings of the National Academy of Sciences of the United States of America·V BUONASSISIA I COHEN

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Citations

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