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Esterase activity of zinc neutral proteases

Biochemistry

Jan 13, 1976

B Holmquist, Bert L Vallee

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Abstract

The hydrolysis of a series of depsipeptides demonstrates that the zinc neutral endopeptidases of bacteria are active esterases. Esters such as BzGly-OPhe-Ala, BzGly-OLeu-Ala, and FA-Gly-OLeu-NH2 are hydrolyzed at rates three- to eightfold slower than are their exact peptide analogues, w...read more

Mentioned in this Paper

Bromides
Vibrio proteolyticus
Proteolytic Enzyme
Sodium
Infrared Spectrophotometry
Structure-Activity Relationship
Enzyme Activation
Zinc
Hydrogen-Ion Concentration
Cytokinesis of the Fertilized Ovum
8
2
Paper Details
References
    • References25
    • Citations27
    • References25
    • Citations27
  • Esterase activity of zinc neutral proteases

    Biochemistry

    Jan 13, 1976

    B Holmquist, Bert L Vallee

    PMID: 2276

    DOI: 10.1021/bi00646a016

    Abstract

    The hydrolysis of a series of depsipeptides demonstrates that the zinc neutral endopeptidases of bacteria are active esterases. Esters such as BzGly-OPhe-Ala, BzGly-OLeu-Ala, and FA-Gly-OLeu-NH2 are hydrolyzed at rates three- to eightfold slower than are their exact peptide analogues, w...read more

    Mentioned in this Paper

    Bromides
    Vibrio proteolyticus
    Proteolytic Enzyme
    Sodium
    Infrared Spectrophotometry
    8
    2
    Paper Details
    References
    • References25
    • Citations27
    • References25
    • Citations27
  • Get paper from

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