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Esterification of all four monoribonucleotides with acetyl-D-L-valine proceeds with a preference for the D-isomer but the D/L ratio in the products declines as a function of the hydrophobicity of the nucleotide

Bioorganic Chemistry

Jan 1, 1992

N S Wickramasinghe, J C Lacey

PMID: 11540890

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Abstract

We recently reported that esterification of 5'-AMP with N-acetyl amino acids proceeds with a preference for D-amino acids, and the D/L ratio in products declines as the hydrophobicity of the amino acid declines. Using one amino acid, Ac-Val, we now show that esterification of all four n...read more

Mentioned in this Paper

Ribonucleotides
Valine
Amino Acids, I.V. solution additive
N-acetylvaline, (L)-isomer
Nucleotides
Phosphaden
Hydrophobic Interactions
Isomerism
Amino Acid [EPC]
Esterification
Paper Details
References
  • References7
  • Citations3
1

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Esterification of all four monoribonucleotides with acetyl-D-L-valine proceeds with a preference for the D-isomer but the D/L ratio in the products declines as a function of the hydrophobicity of the nucleotide

Bioorganic Chemistry

Jan 1, 1992

N S Wickramasinghe, J C Lacey

PMID: 11540890

DOI:

Abstract

We recently reported that esterification of 5'-AMP with N-acetyl amino acids proceeds with a preference for D-amino acids, and the D/L ratio in products declines as the hydrophobicity of the amino acid declines. Using one amino acid, Ac-Val, we now show that esterification of all four n...read more

Mentioned in this Paper

Ribonucleotides
Valine
Amino Acids, I.V. solution additive
N-acetylvaline, (L)-isomer
Nucleotides
Phosphaden
Hydrophobic Interactions
Isomerism
Amino Acid [EPC]
Esterification

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Related Papers

Journal of Molecular Evolution

Chemical esterification of 5'-AMP occurs predominantly at the 2' position

Journal of Molecular EvolutionOctober 1, 1990
J C LaceyC L Watkins
Paper Details
References
  • References7
  • Citations3
1

Download from

PubMed
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