Estimated Brain Tissue Response Following Impacts Associated With and Without Diagnosed Concussion

Annals of Biomedical Engineering
Jonathan G BeckwithRichard M Greenwald

Abstract

Kinematic measurements of head impacts are sensitive to sports concussion, but not highly specific. One potential reason is these measures reflect input conditions only and may have varying degrees of correlation to regional brain tissue deformation. In this study, previously reported head impact data recorded in the field from high school and collegiate football players were analyzed using two finite element head models (FEHM). Forty-five impacts associated with immediately diagnosed concussion were simulated along with 532 control impacts without identified concussion obtained from the same players. For each simulation, intracranial response measures (max principal strain, strain rate, von Mises stress, and pressure) were obtained for the whole brain and within four regions of interest (ROI; cerebrum, cerebellum, brain stem, corpus callosum). All response measures were sensitive to diagnosed concussion; however, large inter-athlete variability was observed and sensitivity strength depended on measure, ROI, and FEHM. Interestingly, peak linear acceleration was more sensitive to diagnosed concussion than all intracranial response measures except pressure. These findings suggest FEHM may provide unique and potentially important ...Continue Reading

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Citations

Jun 18, 2019·Computer Methods in Biomechanics and Biomedical Engineering·Karen TaylorMichael Gilchrist
Oct 9, 2019·Annals of Biomedical Engineering·Bethany RowsonStefan M Duma
Jul 30, 2020·Annals of Biomedical Engineering·J Sebastian GiudiceMatthew B Panzer
May 1, 2020·Frontiers in Bioengineering and Biotechnology·Erin D AndersonDavid F Meaney
Sep 22, 2020·Brain Communications·Allen A ChampagneDouglas J Cook
Nov 25, 2019·Biomechanics and Modeling in Mechanobiology·Shaoju WuSongbai Ji
Nov 1, 2018·Annals of Biomedical Engineering·J Sebastian GiudiceMatthew B Panzer
Nov 1, 2020·Journal of Neurotrauma·Kianoosh GhaziSongbai Ji
Jan 8, 2021·Journal of Biomechanics·Clara KartonT Blaine Hoshizaki
Jan 20, 2021·Journal of the Mechanical Behavior of Biomedical Materials·David A Bruneau, Duane S Cronin

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Software Mentioned

WSUBIM
Explicit
Abaqus
Matlab scripts
Dyna
WHIM
FEHM
HIT System
Simulated Injury Monitor ( SIMon )
SIMon

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.