Estimating acute and chronic exposure of children and adults to chlorpyrifos in fruit and vegetables based on the new, lower toxicology data

Ecotoxicology and Environmental Safety
P MojsakP Kaczyński

Abstract

This paper presents, for the first time, results for chlorpyrifos (CHLP) in Polish fruits and vegetables over the course of a long period of research, 2007-2016, with toxicological aspects. The challenge of this study was to re-evaluate the impact of chlorpyrifos residues in fruit and vegetables on health risk assessed via acute and chronic exposure based on old and new, lower, established values of: Average Daily Intakes (ADIs)/Acute Reference Doses (ARfDs) and Maximum Residue Levels (MRLs). A total of 3 530 samples were collected, and CHLP in the range of 0.005-1.514 mg/kg was present in 10.2% of all samples. The MRL was exceeded in 0.7% of all samples (MRL established in 2009-2015), and recalculation yielded a much greater number of violations for the new MRL (2016), which exceeded 2.9% of all samples. Acute exposure to CHLP calculated according to the old, higher toxicological data (0.10 mg/kg bw/day), does not exceed 14% of its respective ARfDs for adults and both groups of children, but when calculated for incidental cases according to the current value (ARfD 0.005 mg/kg bw) for infants and toddlers, was above 100% of its respective ARfDs in: white cabbage (263.65% and 108.24%), broccoli (216.80% and 194.72%) and apples (...Continue Reading

References

Jul 1, 2008·Toxicology Letters·Alan R BoobisAngelo Moretto
Oct 22, 2008·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Godfred Darko, Osei Akoto
Aug 15, 2009·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·R Mladenova, D Shtereva
Aug 13, 2011·Ecotoxicology and Environmental Safety·Yawar LatifM I Bhanger
Nov 15, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Hye Ran JeongJae Young Cho
Jan 3, 2012·Regulatory Toxicology and Pharmacology : RTP·Chen ChenYun Li
May 7, 2014·Food Chemistry·Gözde Türköz BakırcıSemih Ötleş
Sep 27, 2014·The Science of the Total Environment·Bozena Lozowicka
Nov 25, 2014·American Journal of Respiratory and Critical Care Medicine·Elspeth J HulseMichael Eddleston
Jul 19, 2015·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Bodil Hamborg JensenJens Hinge Andersen
Sep 8, 2015·Regulatory Toxicology and Pharmacology : RTP·Liping FangHuidong Li
Sep 19, 2015·Regulatory Toxicology and Pharmacology : RTP·Sohair A Gad AllaMohamed Tawfic Ahmed
Jan 18, 2016·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Leyre QuijanoOlga Pardo
Jan 4, 2017·Food Additives & Contaminants. Part B, Surveillance·Samira MebdouaGhania Ounane
Sep 1, 2017·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Xiangkun YangMichael G Bartlett

❮ Previous
Next ❯

Citations

May 1, 2019·Environmental Geochemistry and Health·Ming LiYong Yu
Mar 29, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Chung-Pei ChangGeng-Ruei Chang
Mar 25, 2021·Environmental Science and Pollution Research International·İsra ToptanciMohamed Fawzy Ramadan
Jul 8, 2021·Environmental Science and Pollution Research International·Yasser El-Nahhal, Ibrahim El-Nahhal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Food Additives & Contaminants. Part B, Surveillance
Samira MebdouaGhania Ounane
Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
Peggy Drouillet-PinardSaida Barnat
© 2022 Meta ULC. All rights reserved