Estimating Acute Cardiovascular Effects of Ambient PM2.5 Metals

Environmental Health Perspectives
Dongni YeStefanie Ebelt Sarnat

Abstract

Few epidemiologic studies have investigated health effects of water-soluble fractions of PM2.5 metals, the more biologically accessible fractions of metals, in their attempt to identify health-relevant components of ambient PM2.5. In this study, we estimated acute cardiovascular effects of PM2.5 components in an urban population, including a suite of water-soluble metals that are not routinely measured at the ambient level. Ambient concentrations of criteria gases, PM2.5, and PM2.5 components were measured at a central monitor in Atlanta, Georgia, during 1998-2013, with some PM2.5 components only measured during 2008-2013. In a time-series framework using Poisson regression, we estimated associations between these pollutants and daily counts of emergency department (ED) visits for cardiovascular diseases in the five-county Atlanta area. Among the PM2.5 components we examined during 1998-2013, water-soluble iron had the strongest estimated effect on cardiovascular outcomes [R͡R=1.012 (95% CI: 1.005, 1.019), per interquartile range increase (20.46ng/m3)]. The associations for PM2.5 and other PM2.5 components were consistent with the null when controlling for water-soluble iron. Among PM2.5 components that were only measured durin...Continue Reading

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Citations

Apr 22, 2020·Journal of the Air & Waste Management Association·Inkyu HanElaine Symanski
Jan 12, 2021·Atmospheric Chemistry and Physics·Havala O T PyeAndreas Zuend

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