Estimating burden and disease costs of exposure to endocrine-disrupting chemicals in the European union

The Journal of Clinical Endocrinology and Metabolism
Leonardo TrasandeJerrold J Heindel

Abstract

Rapidly increasing evidence has documented that endocrine-disrupting chemicals (EDCs) contribute substantially to disease and disability. The objective was to quantify a range of health and economic costs that can be reasonably attributed to EDC exposures in the European Union (EU). A Steering Committee of scientists adapted the Intergovernmental Panel on Climate Change weight-of-evidence characterization for probability of causation based upon levels of available epidemiological and toxicological evidence for one or more chemicals contributing to disease by an endocrine disruptor mechanism. To evaluate the epidemiological evidence, the Steering Committee adapted the World Health Organization Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group criteria, whereas the Steering Committee adapted definitions recently promulgated by the Danish Environmental Protection Agency for evaluating laboratory and animal evidence of endocrine disruption. Expert panels used the Delphi method to make decisions on the strength of the data. Expert panels achieved consensus at least for probable (>20%) EDC causation for IQ loss and associated intellectual disability, autism, attention-deficit hyperactivity disord...Continue Reading

Citations

Mar 19, 2016·Journal of Thyroid Research·Deborah MolehinKerry Richard
Feb 6, 2016·International Journal of Environmental Research and Public Health·Nicole Bijlsma, Marc M Cohen
Feb 6, 2016·Reviews in Endocrine & Metabolic Disorders·Anna Beronius, Laura N Vandenberg
Jan 31, 2016·Reviews in Endocrine & Metabolic Disorders·Salvatore BenvengaRoberto Vita
Jan 31, 2016·Reviews in Endocrine & Metabolic Disorders·Polyxeni Nicolopoulou-StamatiAnnie J Sasco
Nov 18, 2015·Human Reproduction·Carmen MesserlianUNKNOWN Earth Study Team
Nov 18, 2015·The Lancet. Diabetes & Endocrinology·Robert GiffordMichael Eddleston
Oct 5, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Gian Carlo Di RenzoLinda C Giudice
Feb 2, 2016·American Journal of Obstetrics and Gynecology·Amanda S Janesick, Bruce Blumberg
Sep 21, 2015·Environmental Science and Pollution Research International·Roland WeberJohn Vijgen
Jul 27, 2015·Environmental Monitoring and Assessment·Milica Medic StojanoskaNatasa Milic
May 25, 2016·International Journal of Hygiene and Environmental Health·Martine VrijheidMark Nieuwenhuijsen
Jun 18, 2016·The Lancet. Diabetes & Endocrinology·Jean-Pierre BourguignonR Thomas Zoeller
Jul 1, 2016·Nature Protocols·Helen L BridleAndrea I Schäfer
Jul 15, 2016·Environmental Health : a Global Access Science Source·Laura N VandenbergChristina Rudén
Oct 25, 2016·Environmental Toxicology and Pharmacology·Karolina KowalskaAgnieszka Wanda Piastowska-Ciesielska
Oct 21, 2016·Reproductive Toxicology·Jerrold J HeindelFrederick Vom Saal
Oct 22, 2016·The Lancet. Diabetes & Endocrinology·Michele A La Merrill
Oct 22, 2016·The Lancet. Diabetes & Endocrinology·Teresa M AttinaLeonardo Trasande
Oct 30, 2016·Environment International·Karen TordjmanTamar Berman
Dec 9, 2016·Nature Reviews. Endocrinology·Andreas Kortenkamp
Jul 16, 2016·Journal of Epidemiology and Community Health·Leonardo TrasandeRobert Thomas Zoeller
Oct 30, 2016·Journal of Epidemiology and Community Health·Leonardo TrasandeP Monica Lind
May 27, 2017·Journal of Hazardous Materials·Matteo TagliaviniAndrea Iris Schäfer
May 31, 2017·Current Opinion in Obstetrics & Gynecology·Lidia Mínguez-Alarcón, Audrey J Gaskins
Mar 23, 2017·Journal of Epidemiology and Community Health·Laura N VandenbergJohn Peterson Myers
Sep 8, 2017·International Journal of Molecular Sciences·Do-Yeal RyuMyung-Geol Pang
Oct 5, 2017·International Journal of Environmental Research and Public Health·Hyeri JeongYoungjun Kim
Dec 6, 2017·Environmental Health : a Global Access Science Source·Philippe Grandjean, Martine Bellanger
Sep 9, 2016·New Solutions : a Journal of Environmental and Occupational Health Policy : NS·Symma Finn, Gwen Collman
Sep 25, 2017·Environmental Health Perspectives·Maria S BornmanJerrold J Heindel
Mar 30, 2016·Environmental Health Perspectives·Leonardo TrasandeTeresa M Attina
Sep 13, 2017·Environmental Health Perspectives·Jane MunckeMartin Scheringer
Jul 8, 2016·Environmental Health Perspectives·Md Saidur RahmanMyung-Geol Pang
Nov 9, 2018·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Zhihong ZhangMingzhi Huang
Nov 24, 2018·Environmental Science and Pollution Research International·Shakila SabirAmmara Saleem

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.