Abstract
Allogeneic hematopoietic cell transplantation (HCT) is an increasingly used therapy for many patients with hematologic malignancies and other marrow failure or immune system disorders. The purpose of this study was to quantify and visualize both the demand and unmet need for HCT. HCT use for 2012 was described using the Center for International Blood and Marrow Transplant Research registry. Potential demand for HCT was calculated using 2012 SEER data and published literature for HCT-treatable conditions. Point locations of transplant centers were geocoded using geographic information system (GIS) software; Thiessen polygons were created to establish adult (age 20 to 74 years) and pediatric (age 0 to 19 years) market areas. Market-area population estimates were calculated using 2012 population estimates by age aggregated by census block. US market areas for HCTs were identified separately for transplant centers treating adult (n = 62) and pediatric patients (n = 52). Overall HCT demand among adults was 16,096, with an unmet need for HCTs of 10,276 patients. For pediatric patients, the total demand was 4,561, with an unmet need of 3,213 potential recipients. Evaluation of adult and pediatric market areas indicated that the larges...Continue Reading
References
Jan 1, 1990·Social Science & Medicine·L Twigg
Sep 6, 2002·Seminars in Hematology·Richard M Stone
Mar 7, 2003·Bone Marrow Transplantation·C PetersUNKNOWN Working Party on Inborn Errors, European Bone Marrow Transplant Group
Apr 2, 2003·Annual Review of Public Health·Sara L McLafferty
Jul 13, 2004·Acta Tropica·Peter W GethingRobert W Snow
May 5, 2005·Blood·Martin S TallmanJacob M Rowe
Jul 5, 2005·Blood·Mohamed L SorrorBarry Storer
May 10, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Elihu Estey
Jan 15, 2008·Cancer·Tracy OnegaDavid Goodman
Oct 13, 2009·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·George BuchananShalini Shenoy
Dec 29, 2009·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Navneet S MajhailJ Douglas Rizzo
Jan 28, 2010·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Shu-Chih SuSteven Piantadosi
Jan 29, 2010·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Tracy OnegaDavid Goodman
Jan 15, 2011·Blood·André TichelliJakob R Passweg
Jan 18, 2011·Hematology·William Blum
May 5, 2011·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Navneet S MajhailJ Douglas Rizzo
Sep 13, 2011·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Karim E Abou-NassarPhilippe Armand
Dec 20, 2011·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Navneet S MajhailEdward L Snyder
Jun 19, 2012·Bone Marrow Transplantation·J PidalaC Anasetti
Oct 20, 2012·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Ellen M DenzenElizabeth A Murphy
Jul 3, 2013·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Song YaoPhilip L McCarthy
Jul 25, 2013·Blood·Brian KossJoseph T Opferman
Apr 10, 2014·Journal of Oncology Practice·Jaime M PreusslerNavneet S Majhail
Citations
Sep 26, 2015·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Kelsey BesseMark Albrecht
Oct 13, 2015·Bone Marrow Transplantation·P L Delamater, J P Uberti
May 11, 2016·Human Immunology·Vanja PaunićMartin Maiers
Dec 23, 2017·Bone Marrow Transplantation·Giuseppe MiloneFrancesca Bonifazi
Jun 21, 2019·Journal of Medical Ethics·Andrew HantelMark Siegler
Nov 16, 2019·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nandita KheraNavneet Majhail
Jul 6, 2021·Transplantation and Cellular Therapy·Joseph MockKaren Ballen