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Estimating synonymous and nonsynonymous substitution rates under realistic evolutionary models

Molecular Biology and Evolution

Feb 10, 2000

Ziheng Yang, R Nielsen

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Abstract

Approximate methods for estimating the numbers of synonymous and nonsynonymous substitutions between two DNA sequences involve three steps: counting of synonymous and nonsynonymous sites in the two sequences, counting of synonymous and nonsynonymous differences between the two sequences...read more

Mentioned in this Paper

Metazoa
Theoretical Study
Biological Evolution
2
761
1
Paper Details
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  • Citations767
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Estimating synonymous and nonsynonymous substitution rates under realistic evolutionary models

Molecular Biology and Evolution

Feb 10, 2000

Ziheng Yang, R Nielsen

PMID: 10666704

DOI: 10.1093/oxfordjournals.molbev.a026236

Abstract

Approximate methods for estimating the numbers of synonymous and nonsynonymous substitutions between two DNA sequences involve three steps: counting of synonymous and nonsynonymous sites in the two sequences, counting of synonymous and nonsynonymous differences between the two sequences...read more

Mentioned in this Paper

Metazoa
Theoretical Study
Biological Evolution
2
761
1

Feeds With Similar Papers

Parasite evolution

Parasite evolution involves the heritable genetic changes that a parasite accumulates during its life time. Discover the latest research on parasite evolution here.

Related Papers

Computer Applications in the Biosciences : CABIOS

PAML: a program package for phylogenetic analysis by maximum likelihood

Computer Applications in the Biosciences : CABIOSNovember 21, 1997
Ziheng Yang
Molecular Biology and Evolution

PAML 4: phylogenetic analysis by maximum likelihood

Molecular Biology and EvolutionMay 8, 2007
Ziheng Yang
Paper Details
References
  • References12
  • Citations767
12
  • References12
  • Citations767
12345...

Download from

Publisher
PubMed
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