Estimating the influence of attention on population codes in human visual cortex using voxel-based tuning functions

NeuroImage
John T SerencesL Tugan Muftuler

Abstract

In order to form stable perceptual representations, populations of sensory neurons must pool their output to overcome physiological noise; selective attention is then required to ensure that behaviorally relevant stimuli dominate these 'population codes' to gain access to awareness. However, the role that attention plays in shaping population response profiles has received little direct investigation, in part because most traditional neurophysiological methods cannot simultaneously assess changes in activity across large populations of sensory neurons. Based on single-unit recording studies, current theories hold that attending to a relevant feature sharpens the population response profile and improves the signal-to-noise ratio of the resulting perceptual representation. Here, we test this hypothesis using fMRI and an analysis approach that is able to estimate the influence of feature-based attentional modulations on population response profiles. We first derive orientation tuning functions for single voxels in human primary visual cortex, and then use these tuning functions to sort voxels according to their orientation preference. We then show that selective attention systematically biases population response profiles so that ...Continue Reading

Citations

Sep 13, 2012·Nature Communications·Jason Fischer, David Whitney
Jan 21, 2012·International Journal of Neural Systems·Wei-Yen Hsu
Jul 16, 2010·Journal of Neurophysiology·Miranda Scolari, John T Serences
Dec 25, 2009·Journal of Neurophysiology·Andrew S KayserMark D'Esposito
May 21, 2010·Journal of Neurophysiology·Sameer Saproo, John T Serences
Apr 23, 2010·Journal of Neurophysiology·John T Serences, Sameer Saproo
Jul 1, 2010·Journal of Cognitive Neuroscience·Brian T MillerMark D'Esposito
May 31, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·David E AndersonEdward Awh
Jun 8, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Tiffany HoJohn T Serences
Sep 9, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Joo-Hyun SongAlex R Wade
Apr 19, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Caterina GrattonMark D'Esposito
Dec 4, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Edward F EsterEdward Awh
Jan 8, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jascha D SwisherFrank Tong
Apr 1, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jeremy FreemanElisha P Merriam
Jul 19, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jiaxiang ZhangJames B Rowe
Jun 1, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Miranda ScolariJohn T Serences
Nov 24, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Janneke F M JeheeFrank Tong
Oct 23, 2013·Journal of Cognitive Neuroscience·Yaara Erez, Galit Yovel
Apr 4, 2014·Experimental Brain Research·Nikolaos SmyrnisIoannis Evdokimidis
Nov 22, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jiefeng JiangTobias Egner
Dec 18, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jeremy FreemanElisha P Merriam
Dec 4, 2009·Proceedings of the National Academy of Sciences of the United States of America·Leila ReddyRufin VanRullen
Nov 11, 2015·Attention, Perception & Psychophysics·Peng SunGeorge Sperling
Jun 21, 2015·NeuroImage·Ryan T Maloney, Colin W G Clifford
Oct 27, 2015·Nature Neuroscience·Ruben S van BergenJanneke F M Jehee
Jun 7, 2013·Annals of the New York Academy of Sciences·Tyler Davis, Russell A Poldrack
May 10, 2011·Vision Research·Marisa Carrasco
May 15, 2012·Vision Research·Katrin HerrmannMarisa Carrasco
Feb 22, 2014·Cerebral Cortex·Vadim AxelrodGalit Yovel
Jul 6, 2014·Brain Structure & Function·Sam LingFranco Pestilli
Jul 15, 2009·NeuroImage·Justin L Gardner
Feb 25, 2014·Neuropsychologia·Scott A Reed, Paul Dassonville
Mar 15, 2015·Trends in Cognitive Sciences·Thomas C SpragueJohn T Serences
Jan 21, 2015·Cerebral Cortex·Joset A EtzelTodd S Braver
Jun 3, 2016·Cerebral Cortex·S FerriG A Orban

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