Estimating the risk of dengue transmission from Dutch blood donors travelling to Suriname and the Dutch Caribbean

Vox Sanguinis
Welling OeiMart P Janssen

Abstract

The risk of dengue transmitted by travellers is known. Methods to estimate the transmission by transfusion (TT) risk from blood donors travelling to risk areas are available, for instance, the European Up-Front Risk Assessment Tool (EUFRAT). This study aimed to validate the estimated risk from travelling donors obtained from EUFRAT. Surveillance data on notified dengue cases in Suriname and the Dutch Caribbean islands (Aruba, Curaçao, St. Maarten, Bonaire, St. Eustatius and Saba) in 2001-2011 was used to calculate local incidence rates. Information on travel and donation behaviour of Dutch donors was collected. With the EUFRAT model, the TT risks from Dutch travelling donors were calculated. Model estimates were compared with the number of infections in Dutch travellers found by laboratory tests in the Netherlands. The expected cumulative number of donors becoming infected during travels to Suriname and the Dutch Caribbean from 2001 to 2011 was estimated at 5 (95% CI, 2-11) and 86 (45-179), respectively. The infection risk inferred from the laboratory-based study was 19 (9-61) and 28 (14-92). Given the independence of the data sources, these estimates are remarkably close. The model estimated that 0·02 (0·001-0·06) and 0·40 (0·...Continue Reading

References

Dec 9, 2008·The Medical Clinics of North America·Annelies Wilder-Smith, Duane J Gubler
May 3, 2011·Emerging Infectious Diseases·Gijs G G BaatenAnneke van den Hoek
Nov 2, 2012·Transfusion·Welling OeiMirjam E E Kretzschmar
Aug 31, 2013·Clinical Epidemiology·Natasha Evelyn Anne MurrayAnnelies Wilder-Smith
Jul 24, 2014·Transfusion·Ryanne W Lieshout-KrikkePieternel C M Pasker-de Jong
Jan 22, 2015·Transfusion·José Eduardo LeviAlfredo Mendrone
Feb 26, 2016·The Journal of Infectious Diseases·Ester C SabinoUNKNOWN International Component of the NHLBI Recipient Epidemiology and Donor Evaluation Study-III

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Citations

Mar 2, 2021·Frontiers in Neurology·Thomas LangerakEric C M van Gorp
Apr 27, 2021·Vox Sanguinis·Rossana C Garzon JimenezMart P Janssen

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