Estimation of diagnostic test characteristics and prevalence of Giardia duodenalis in dairy calves in Belgium using a Bayesian approach

International Journal for Parasitology
T GeurdenD Berkvens

Abstract

A Bayesian approach was used to determine both the test properties of three diagnostic test procedures and the prevalence of Giardia duodenalis in dairy calves in Belgium. A cross-sectional survey was conducted in the province of East Flanders, Belgium. Between September 2001 and December 2003, a total of 100 farms were visited and faecal samples were obtained rectally from 499 calves aged from newborn to 70 days. Because there is no gold standard for the diagnosis of a G. duodenalis infection in dairy calves, a subset of 235 samples obtained on the first 50 farms, was examined using three different assays: microscopical examination, an immunofluorescence assay (IFA) and an antigen detecting Elisa (ELISA). Based on the results of these three tests, Bayesian analysis indicated that the prevalence of G. duodenalis in dairy calves was 0.19 (95% Confidence Interval: 0.11-0.28) and that ELISA (Sensitivity (Se) 0.89 and Specificity (Sp): 0.90) and IFA (Se: 0.77 and Sp: 0.95) were both sensitive and specific diagnostic techniques, whereas microscopical examination was less sensitive (Se: 0.56 and Sp: 0.87). The proportion of positive farms was estimated as 0.42 (0.24-0.62). The prevalence and the cyst excretion in calves from differen...Continue Reading

References

Jul 1, 1990·The Journal of Infectious Diseases·A BuretM E Olson
Mar 1, 1997·Veterinary Parasitology·M E OlsonT A McAllister
Oct 11, 2001·American Journal of Veterinary Research·D V NydamH O Mohammed
Nov 14, 2001·Veterinary Parasitology·R E HuetinkH W Ploeger
Jan 30, 2004·Trends in Parasitology·María-Gloria BasáñezLawrence Joseph

❮ Previous
Next ❯

Citations

Jan 15, 2011·Clinical Microbiology Reviews·Yaoyu Feng, Lihua Xiao
Jun 23, 2010·Acta Veterinaria Scandinavica·Miguella P Mark-CarewHussni O Mohammed
Apr 17, 2009·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Thomas GeurdenEdwin Claerebout
Mar 24, 2012·Folia Parasitologica·Flávio Medeiros Paz e SilvaJoão Pessoa Araújo
Jan 23, 2016·Veterinary Parasitology·Cliff KakandelwaIsaac G K Phiri
Mar 17, 2009·Experimental Parasitology·Thomas GeurdenEdwin Claerebout
Mar 11, 2008·Veterinary Parasitology·T GeurdenJ Vercruysse
Jun 15, 2007·Veterinary Parasitology·Emmanuel LesaffreDirk Berkvens
Sep 10, 2011·Veterinary Parasitology·G H GritT Geurden
Jan 27, 2015·Environmental Monitoring and Assessment·Amimul EhsanEdwin Claerebout
Aug 2, 2008·Cadernos de saúde pública·Sheila Maria Alvim MatosMaurício Lima Barreto
Jan 18, 2006·Veterinary Parasitology·Franz J Conraths, Gereon Schares
Mar 19, 2008·Animal Health Research Reviews·Locksley L McV MessamIan A Gardner
Aug 23, 2019·Comparative Immunology, Microbiology and Infectious Diseases·Katharina LichtmannspergerThomas Wittek

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.