PMID: 8972108Dec 1, 1996Paper

Estimation of dietary exposure to chemicals: a case study illustrating methods of distributional analyses for food consumption data

Risk Analysis : an Official Publication of the Society for Risk Analysis
J H DriverG K Whitmyre

Abstract

There are a number of sources of variability in food consumption patterns and residue levels of a particular chemical (e.g., pesticide, food additive) in commodities that lead to an expected high level of variability in dietary exposures across a population. This paper focuses on examples of consumption pattern survey data for specific commodities, namely that for wine and grape juice, and demonstrates how such data might be analyzed in preparation for performing stochastic analyses of dietary exposure. Data from the NIAAA/NHIS wine consumption survey were subset for gender and age group and, with matched body weight data from the survey database, were used to define empirically-based percentile estimates for wine intake (microliter wine/kg body weight) for the strata of interest. The data for these two subpopulations were analyzed to estimate 14-day consumption distributional statistics and distributions for only those days on which wine was consumed. Data subsets for all wine-consuming adults and wine-consuming females ages 18 through 45, were determined to fit a lognormal distribution (R2 = 0.99 for both datasets). Market share data were incorporated into estimation of chronic exposures to hypothetical chemical residues in i...Continue Reading

Citations

Mar 15, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·R KroesA Visconti
Oct 14, 2003·Food Additives and Contaminants·M B GilsenanM J Gibney
Jul 20, 2005·International Journal of Environmental Health Research·Judicate P Ndengerio-Ndossi, Geoff Cram
Jul 17, 1998·Risk Analysis : an Official Publication of the Society for Risk Analysis·H L JacobsD B Phan
Dec 22, 1999·Regulatory Toxicology and Pharmacology : RTP·M R LöwikC Kistemaker
May 4, 2004·Pest Management Science·Denis HamiltonUNKNOWN of the International Union of Pure and Applied Chemistry

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