Estimation of maximum ventricular elastance under assistance with a rotary blood pump

Artificial Organs
Telma Keiko SugaiAtsushi Baba

Abstract

The maximum ventricular elastance is a reliable index for assessing the cardiac function from changes in its pressure-volume relationship. The advantage of this index is that it can represent the contractility of either unassisted hearts or native hearts assisted with rotary blood pumps. However, there are situations in which changes in the ventricular load required for the conventional estimation method might be risky. For example, in a bridge-to-recovery the cardiac function should also be continuously observed after the implantation of a rotary blood pump. In this article, we present the results of the estimation of the maximum elastance with in vivo data using the parameter optimization method, which is a single-beat estimation method. The estimated values for the normal cardiac function (6.8 +/- 0.6, 4.5 +/- 0.9, 4.2 +/- 1.8 mm Hg/mL) were significantly different from those for the low cardiac function (3.2 +/- 1.5, 1.9 +/- 1.0, 1.9 +/- 1.2 mm Hg/mL) from the data of the three animals that were analyzed. Besides, the maximum elastance values were independent of the pump rotational speed. These results indicate that this index might be useful for the detection of the myocardial recovery.

References

Mar 27, 2001·The Annals of Thoracic Surgery·R HetzerM Dandel
Apr 18, 2002·American Journal of Physiology. Heart and Circulatory Physiology·Knut E KjørstadTruls Myrmel
Jul 15, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Daniel BurkhoffHiroyuki Suga
Jan 27, 2006·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Stijn VandenberghePascal Verdonck
Oct 20, 2007·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·Daisuke OgawaMakoto Yoshizawa

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Citations

Mar 16, 2011·Artificial Organs·Paul S Malchesky
Jun 24, 2014·Heart, Lung & Circulation·Abraham E WeiMark A Lovich
Nov 13, 2021·Frontiers in Cardiovascular Medicine·Jean BonnemainLucas Liaudet

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