Estimation of severity of stenosis with a Doppler guide wire in the experimental models

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
T HozumiT Akasaka

Abstract

Application of the continuity equation to Doppler catheter measurement of quantitative coronary flow velocity has been reported recently to be one of the accurate methods to evaluate mild to moderate coronary stenosis. This method, however, has not been validated in moderate to severe coronary stenosis. Furthermore, the ratio of prestenotic velocity/stenotic velocity may be influenced by side branches proximal to moderate to severe stenosis. Therefore we designed this study to evaluate the accuracy of the continuity equation method in the assessment of moderate to severe stenosis by an 0.018-inch (0.46 mm) Doppler guide wire (12 MHz) and the influence of a side branch on estimation of stenotic severity. Doppler spectra were recorded in the straight rigid tubes (4 mm diameter) with different severities of stenosis (50%, 62.5%, and 75% diameter stenosis) without a side branch with a Doppler guide wire. By the continuity equation, percent diameter stenosis was calculated from the proximal/stenotic and distal/stenotic velocity ratios in each model at different flow rates. In the model of 75% diameter stenosis with a side branch (1 mm diameter) proximal to the stenosis and the model of 75% diameter stenosis with a side branch (1 mm ...Continue Reading

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