PMID: 8947335Nov 1, 1996Paper

Estimation of skin prick test reactions with a scanning program

Allergy
H PijnenborgS Dreborg

Abstract

We evaluated a new method of computer-based scanning of skin prick test wheal areas. To test the calibration of the program, we scanned five constructed circles of exactly defined areas between 5 and 255 mm2. One of these circles was scanned in different degrees of contrast (modes), the middle mode being used in the other experiments. We also investigated the inter- and intraoperator variation. Finally, results obtained by measuring diameters of wheals and by the new method of area determination were compared for 82 histamine and 75 egg wheals. The areas found agreed well with the real areas (P < 0.01) (mean 97.4-100.8%), except for the smallest wheal (5mm2) (NS). Areas obtained in the "middle position" closely resembled the real area. The intraoperator coefficient of variation (c.v.) was 1.4% (0.3-4.3), the day-to-day c.v. was 1.9% (0.2-5.3), and the interoperator c.v. was 2.3% (0.7-5.7), with a higher c.v. for small areas. Histamine and egg wheals were significantly larger with the diameter method (126% and 129%, respectively) than with the area method. The difference between the methods was most pronounced for small wheal areas. The c.v. of the scanning method was significantly lower than that of the diameter method. The new...Continue Reading

References

Mar 1, 1990·The Journal of Allergy and Clinical Immunology·K J SimonsF E Simons
Aug 1, 1990·The Journal of Allergy and Clinical Immunology·R OlsonB Zweiman
Nov 1, 1989·Allergy·I VohlonenO P Heinonen
Jan 1, 1989·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·U PipkornL Enerbäck
Jan 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L K PoulsenH J Malling

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Citations

Jan 31, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Yael GraifArnon Goldberg
Sep 12, 2000·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·A AnticoB Morrica
Dec 12, 2001·Allergy·F A Bahmer
Feb 26, 2016·Clinical and Translational Allergy·J P M van der ValkN W de Jong
Jan 26, 2006·Experimental Dermatology·Stefan WöhrlMichael Prinz
Jul 19, 2008·Experimental Dermatology·Heikki Lamminen, Ville Voipio
Mar 22, 2007·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Rosaly Vieira dos SantosHermênio Cavalcante Lima
Aug 7, 2008·Clinical and Experimental Dermatology·R V dos SantosM Maurer
Apr 24, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·N W de JongR Gerth van Wijk
Apr 22, 2016·Allergy·X JustoG Gastaminza
Jan 27, 1999·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·P A Eigenmann, H A Sampson

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