PMID: 1195348Jan 1, 1975Paper

Estimation of surface charges in some biological membranes

The Journal of Membrane Biology
N Lakshminarayanaiah, K Murayama

Abstract

The resting membrane potential data existing in the literature for the giant axon of the squid, frog muscle and barnacle muscle have been analyzed from the standpoint of the theory of membrane potential due to Kobatake and co-workers. The average values derived for the effective charge density phi chi (where phi is a constant, 0 less than phi less than 1, and represents the fraction of counterions that are free, and chi is the stoichiometric charge density in the membrane) present on the different biomembranes existing in their normal ionic environment are 0.3, 0.325 and 0.17 M for the squid axon, frog and barnacle muscles, respectively. On the assumption that the values of phi are 0.4 and 0.2 for nerve and muscle membranes, respectively, values of 0.75, 1.62 and 0.85 M have been derived for the stoichiometric charge density (chi) present in the respective biological membranes. These correspond to 1 negative charge per 222, 103 and 195 A2 of the membrane area of the squid axon, frog and barnacle muscles, respectively.

References

Apr 23, 1975·The Journal of Membrane Biology·N Lakshminarayaniah
Jun 1, 1972·Journal of Bioenergetics·R J Baskin
Jan 1, 1974·The Journal of Membrane Biology·N Lakshminarayanaiah
Jun 1, 1973·The Journal of General Physiology·B Hille
Jun 1, 1973·The Journal of General Physiology·A M Woodhull
Dec 1, 1973·Experientia·W Vogel
Apr 1, 1968·Biophysical Journal·J R Segal
Apr 1, 1967·The Journal of Physiology·R Elul
Apr 28, 1955·The Journal of Physiology·A L HODGKIN, R D KEYNES
Oct 1, 1959·The Journal of Physiology·A L HODGKIN, P HOROWICZ
Jul 20, 1936·The Journal of General Physiology·T Teorell

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Citations

Mar 1, 1980·Archives of Toxicology·E PfaffH Höke
Nov 22, 1976·The Journal of Membrane Biology·N Lakshminarayanaiah
Oct 1, 1977·The Journal of Membrane Biology·K F Schnell
Feb 14, 2017·Nano Convergence·Md Abdul KafiJeong-Woo Choi
Jan 1, 1977·Bulletin of Mathematical Biology·N Lakshminarayanaiah
Mar 15, 2020·Physical Review. E·Aymar C L de LichterveldeMartin Z Bazant

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