Estimation of the hemodynamic response in event-related functional MRI: Bayesian networks as a framework for efficient Bayesian modeling and inference

IEEE Transactions on Medical Imaging
Guillaume MarrelecHabib Benali

Abstract

A convenient way to analyze blood-oxygen-level-dependent functional magnetic resonance imaging data consists of modeling the whole brain as a stationary, linear system characterized by its transfer function: the hemodynamic response function (HRF). HRF estimation, though of the greatest interest, is still under investigation, for the problem is ill-conditioned. In this paper, we recall the most general Bayesian model for HRF estimation and show how it can beneficially be translated in terms of Bayesian graphical models, leading to 1) a clear and efficient representation of all structural and functional relationships entailed by the model, and 2) a straightforward numerical scheme to approximate the joint posterior distribution, allowing for estimation of the HRF, as well as all other model parameters. We finally apply this novel technique on both simulations and real data.

References

Nov 13, 1998·NeuroImage·G K AguirreM D'esposito
Feb 24, 2001·IEEE Transactions on Medical Imaging·C GoutteL K Hansen
Jan 22, 2003·Trends in Neurosciences·Kâmil UğurbilDae Shik Kim
Oct 14, 2003·IEEE Transactions on Medical Imaging·Philippe CiuciuHabib Benali
Nov 5, 2003·Nature Reviews. Neuroscience·Mark D'EspositoAdam Gazzaley

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Citations

Oct 4, 2011·Journal of Medical Systems·Kavishwar B WagholikarAshok W Deshpande
Nov 10, 2006·Journal of Neurophysiology·Elisha P MerriamCarol L Colby
Jul 24, 2007·Medical Image Analysis·J Cohen-AdadF Lesage
Jun 24, 2014·IEEE Transactions on Medical Imaging·Adnan Shah, Abd-Krim Seghouane
Oct 26, 2012·IEEE Transactions on Medical Imaging·Lotfi ChaariPhilippe Ciuciu
Mar 31, 2010·IEEE Transactions on Medical Imaging·Thomas VincentPhilippe Ciuciu
Sep 9, 2011·IEEE Transactions on Medical Imaging·Abd-Krim Seghouane, Adnan Shah
Jan 22, 2008·NeuroImage·Leigh A JohnstonGary F Egan
Jun 6, 2013·NeuroImage·Solveig BadilloPhilippe Ciuciu
Oct 28, 2008·NeuroImage·Catie ChangGary H Glover
Sep 24, 2005·Physics in Medicine and Biology·Yiheng ZhangDavid A Boas

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