Estimation of visual outcome without treatment in patients with subfoveal choroidal neovascularization in pathologic myopia.

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Ariko KojimaManabu Mochizuki

Abstract

To clarify prognostic factors of long-term visual outcome without treatment in patients with myopic choroidal neovascularization (CNV) and estimate a regression equation to predict visual acuity at 5 years after CNV onset. Fifty-four eyes of 54 consecutive patients with high myopia and subfoveal CNV who did not receive treatment were identified using clinical records from 1988 to 2004. Photodynamic therapy not approved for myopic CNV in Japan during this period. The association of best-corrected visual acuity (BCVA) at 5 years after CNV onset with patient age, refractive error, axial length, initial BCVA, myopic retinopathy grade, duration of persistent hemorrhage, CNV size at onset, and size of hemorrhage around the CNV was analyzed using Spearman's correlation and multiple linear regression analysis. BCVA at 5 years after onset was significantly associated with patient age, CNV size, and initial BCVA (P<0.05, Spearman's correlation). The regression equation estimating BCVA at 5 years after CNV onset was based on age and initial BCVA (R2=0.43). When subjects were divided into groups according to age (<40 and >or=40 years), CNV size, axial length and duration of persistent hemorrhage influenced BCVA at 5 years in patients under...Continue Reading

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Citations

Jan 30, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Bogomil VoykovFocke Ziemssen
Jul 21, 2011·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Chih-Hsin ChenHsi-Kung Kuo
Jan 16, 2016·Progress in Retinal and Eye Research·Kyoko Ohno-MatsuiChiu Ming Gemmy Cheung
Jun 24, 2011·American Journal of Ophthalmology·Natsuko NagaokaKyoko Ohno-Matsui
Sep 10, 2011·Clinical & Experimental Ophthalmology·Danny S NgClement W Chan
Sep 9, 2008·American Journal of Ophthalmology·Magda GharbiyaCorrado Balacco Gabrieli
Jul 6, 2014·The British Journal of Ophthalmology·Tien Y WongAdnan Tufail
Jul 2, 2016·Drugs·Kelvin Yi Chong TeoChui Ming Gemmy Cheung
Oct 24, 2017·Asia-Pacific Journal of Ophthalmology·Danny S C NgKyoko Ohno-Matsui
Oct 9, 2015·Eye & Contact Lens·Nicole Shu-Wen ChanChui Ming Gemmy Cheung
Aug 3, 2016·Retina·Timothy Y Y Lai, Chui Ming Gemmy Cheung
Oct 30, 2016·European Journal of Ophthalmology·Nicolas LevezielMarie Noelle Delyfer
Oct 3, 2020·Expert Opinion on Biological Therapy·Danny S C NgTimothy Y Y Lai
Apr 29, 2021·Investigative Ophthalmology & Visual Science·Kyoko Ohno-MatsuiJost B Jonas
Nov 28, 2021·Pharmaceutics·David Blánquez-MartínezCristina Lucía Dávila-Fajardo

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