PMID: 3745474Aug 1, 1986Paper

Estimations of serum arabinitol for diagnosing invasive candidosis

Journal of Clinical Pathology
A G Deacon

Abstract

Arabinitol concentrations were determined in 157 serum samples from 95 patients with suspected invasive candidosis and in 10 serum samples from healthy laboratory workers. Fifty eight of the 95 patients, subsequently diagnosed as not having invasive candidosis had concentrations of arabinitol below 1.2 micrograms/ml (mean 0.59 (SD) 0.26). Sera from the healthy laboratory workers gave similar results (mean 0.55 (0.05]. Concentrations above the normal range were found in 18 of the 19 cases of confirmed or probable invasive candidosis and in seven of eight patients with infected intravenous lines or cannulas and clinical evidence of systemic infection. Raised concentrations were also seen in 10 other patients, including nine with renal failure who did not have invasive infections. Multiple serum samples obtained from 33 patients showed that sequential estimations were of value for diagnosing a developing infection. Despite some difficulties of interpretation the technique is rapid and specific and is suitable for use in the diagnostic laboratory of a larger general hospital.

References

May 7, 1977·British Medical Journal·R C WarrenL O White
Nov 1, 1974·The Journal of Clinical Investigation·G G MillerC E Davis
Aug 1, 1969·The Journal of Infectious Diseases·P D HartJ S Remington
May 1, 1984·Reviews of Infectious Diseases·L de Repentigny, E Reiss
Mar 1, 1983·The Journal of Infectious Diseases·J W GoldD Armstrong
Apr 1, 1983·European Journal of Clinical Microbiology·L O GentryM F Price
May 1, 1981·The Journal of Infectious Diseases·R H EngM Buse

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Citations

May 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·L LehtonenO P Lehtonen
Dec 1, 1987·European Journal of Clinical Microbiology·J RobozJ F Holland
Feb 1, 1990·Acta Odontologica Scandinavica·I Olsen, A Stenderup
Sep 1, 1993·Journal of Clinical Microbiology·J GutiérrezJ A Perez

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