PMID: 3764648Nov 1, 1986Paper

Estrogen and progesterone receptors in meningiomas

Surgical Neurology
F MaiuriB Gallicchio

Abstract

Estradiol and progesterone receptors were studied in 14 patients with meningiomas. Estrogen receptors were detected by specific monoclonal antibodies, whereas progesterone receptors were assayed by the dextran-coated charcoal method. In 9 cases the estrogen receptors were also investigated in cultured tumor cells. Positive estrogen and progesterone receptors were found in 86% of patients. The results have been compared with 11 published series of sex steroid assays in meningiomas. The different rate of positive results in most series can be explained by preoperative glucocorticoid therapy. There is no correlation between the estrogen and progesterone receptor activity, the sex and age of the patients, and the location and histological features of the meningioma. The authors suggest that assays of antiestrogen and antiprogestin drugs in cultured cells can indicate whether this estrogen and progesterone receptor activity may be of therapeutic use.

References

Nov 1, 1979·The New England Journal of Medicine·E R DeSombreM B Lipsett
Feb 15, 1982·Cancer·L L TilzerK Alward
Dec 1, 1981·Neurosurgery·R L MartuzaR G Ojemann
May 15, 1981·Cancer·E V Jensen
May 1, 1958·Journal of Neurology, Neurosurgery, and Psychiatry·E R BICKERSTAFFI A GUEST
Jan 1, 1950·Archives of Neurology and Psychiatry·C W RAND, M ANDLER

❮ Previous
Next ❯

Citations

Sep 2, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Ann Shung LieuShen Long Howng
Nov 1, 1990·Journal of Neurosurgery·P PaolettiG Robustelli della Cuna
Jan 1, 1987·Clinical Neurology and Neurosurgery·J BoitenR de Graaff
Jul 11, 2019·British Journal of Neurosurgery·Francesco MaiuriGiuseppe Mariniello
Apr 1, 1993·Neurosurgery·P M Black
Feb 5, 2021·BMJ : British Medical Journal·Alain WeillJoël Coste
Dec 29, 2020·Frontiers in Oncology·Francesco MaiuriMarialaura Del Basso De Caro
Aug 3, 2021·Frontiers in Oncology·Francesco MaiuriMarialaura Del Basso De Caro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.