PMID: 9164826Jun 1, 1997Paper

Estrogen, progesterone and testosterone receptors in human fetal cartilaginous tissue: immunohistochemical studies

Calcified Tissue International
H Ben-HurA Ornoy

Abstract

Computerized image analysis was used to study the distribution in cartilage of receptors to estrogen, progesterone, and testosterone during human fetal development. We have examined three histologically distinct cell groups (hypertrophic, proliferating, and reserve zones) in long bones, vertebrae, and trachea from 19 fetuses. Comparisons were made across gender and gestational age. Contrasting with controls, we examined the density of receptors, the size of the nuclear area in which the receptors were detected, the number of hormone receptor-bearing cells, and the total receptor quantity per sample. We found that estrogen, progesterone, and testosterone receptors were detected in the nuclei of all cell types, in both female and male embryonic cartilaginous tissue. Gender differences were small and inconsistent. Changes associated with gestational age depicted a pattern of hormone receptor manifestation, shifting from the immature cell types to more differentiated cells. This was evident from the receptor densities and from the cellular area in which receptors were sighted. These dynamics are accompanied by a general increase in receptor content per sample, brought about by the concomitant increase in receptor containing area si...Continue Reading

Citations

Nov 2, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D L S DanilovicI J P Arnhold
Jun 9, 2001·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·H ClaassenB Kurz
Jul 1, 1999·Cardiovascular Surgery : Official Journal of the International Society for Cardiovascular Surgery·A MashiahH Ben-Hur
Aug 7, 2012·Rheumatology·Shuying WeiChanghai Ding
Nov 18, 2004·The Journal of Craniofacial Surgery·Ines C LinRichard E Kirschner
Jul 14, 2005·Proceedings. Biological Sciences·Matthew H McIntyreBradford Towne
Mar 1, 2006·Reproductive Biology and Endocrinology : RB&E·Matthew H McIntyre
Apr 17, 2012·The International Journal of Biochemistry & Cell Biology·Geneviève Morrow, Robert M Tanguay
Jan 22, 2011·Progress in Histochemistry and Cytochemistry·Horst ClaassenFriedrich Paulsen
Nov 11, 2008·Steroids·Bart L Clarke, Sundeep Khosla
Dec 25, 2007·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Edward W Carney, Carole A Kimmel
Jul 25, 2007·Clinical Endocrinology·R J PerryS F Ahmed
Jan 29, 2014·American Journal of Human Biology : the Official Journal of the Human Biology Council·Kalliopy Valla, Demetrios J Halazonetis
Oct 15, 2005·American Journal of Physical Anthropology·Matthew H McIntyrePeter T Ellison
Nov 24, 1999·Osteoarthritis and Cartilage·T UshiyamaS Hukuda
Nov 18, 2008·Osteoarthritis and Cartilage·W WangS Kapila
Nov 26, 2011·Progress in Neurobiology·Bernd LenzJohannes Kornhuber
Feb 28, 2009·The Annals of Otology, Rhinology, and Laryngology·Douglas R JohnstonMarc R Rosen
Sep 13, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Harry M RobertsJeanette M Thom
Dec 19, 2019·British Journal of Neurosurgery·Serdar ÇevikHakan Hanımoğlu
Jun 8, 2004·Endocrine Reviews·Dirk VanderschuerenClaes Ohlsson
Feb 22, 2000·The Journal of Bone and Joint Surgery. American Volume·R S SellersE A Morris

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Archives of Sexual Behavior
Robert P BurrissEmma C Nelson
The Journal of Steroid Biochemistry and Molecular Biology
O BlanchardM T Corvol
Postgraduate Medical Journal
M B Ray
© 2021 Meta ULC. All rights reserved