Estrogen receptor ligands. Part 7: Dihydrobenzoxathiin SERAMs with bicyclic amine side chains

Bioorganic & Medicinal Chemistry Letters
Timothy A BlizzardMilton L Hammond

Abstract

A series of benzoxathiin SERAMs with bicyclic amine side chains was prepared. Minor modifications in the side chain resulted in significant effects on biological activity, especially in uterine tissue.

References

Jun 11, 1996·Proceedings of the National Academy of Sciences of the United States of America·G G KuiperJ A Gustafsson
Feb 12, 1998·Proceedings of the National Academy of Sciences of the United States of America·T A GreseJ A Dodge
Nov 2, 2001·Journal of Medicinal Chemistry·D S MortensenJ A Katzenellenbogen
Dec 3, 2002·Journal of Medicinal Chemistry·Brad R HenkeMillard H Lambert
Jun 26, 2003·Bioorganic & Medicinal Chemistry Letters·Chris P MillerHeather A Harris
Jul 25, 2003·Bioorganic & Medicinal Chemistry·Richard J EdsallRichard E Mewshaw
Dec 4, 2003·Bioorganic & Medicinal Chemistry Letters·Nobuhide WatanabeJun-ichi Tsuji
Apr 28, 2004·Bioorganic & Medicinal Chemistry Letters·Helen Y ChenMilton L Hammond
May 6, 2004·Bioorganic & Medicinal Chemistry Letters·Seongkon KimMilton L Hammond

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Citations

Mar 5, 2005·Bioorganic & Medicinal Chemistry Letters·Qiang TanMilton L Hammond
Mar 19, 2011·Journal of Medicinal Chemistry·Nicholas A Meanwell
May 14, 2008·Proceedings of the National Academy of Sciences of the United States of America·Susie Y DaiPatrick R Griffin
Mar 14, 2007·Journal of Molecular Graphics & Modelling·Lívia de B SalumAdriano D Andricopulo
Jul 1, 2004·Bioorganic & Medicinal Chemistry Letters·Timothy A BlizzardMilton L Hammond
Dec 8, 2004·Bioorganic & Medicinal Chemistry Letters·Timothy A BlizzardMilton L Hammond
Oct 1, 2011·Chemistry : a European Journal·Caterina ViglianisiStefano Menichetti
Sep 11, 2008·Chemical Reviews·Alberto BrandiFranca M Cordero
Jul 19, 2018·Chemical Research in Toxicology·Tien-Yi HouMax K Leong
Aug 17, 2019·ACS Medicinal Chemistry Letters·Sébastien L DegorceJames S Scott

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