PMID: 18727894Aug 30, 2008Paper

Etanercept as a possible trigger of fatal pulmonary fibrosis

Archivos de bronconeumología
Juan M Díez PiñaM Paz Rodríguez Bolado

Abstract

Pulmonary fibrosis can be caused by external agents, including certain drugs. For some time now, tumor necrosis factor antagonists such as etanercept have been used to treat certain autoimmune diseases. Fibrosis caused by medication responds to withdrawal of the drug and treatment with corticosteroids. Very rarely, fibrosis is irreversible. We present the case of a patient who developed pulmonary fibrosis after initiating treatment with etanercept. The clinical course was fulminant despite withdrawal of the drug and high doses of corticosteroids.

References

Jan 16, 2002·Annals of Internal Medicine·Davey Smith, Scott Letendre
Apr 19, 2002·The Journal of Pharmacology and Experimental Therapeutics·Bernie ScallonCarrie Wagner
Nov 12, 2002·Chest·Laura Peno-GreenSteven Brantley
Nov 19, 2004·International Journal of Clinical Oncology·Fumiyoshi OhyanagiYasutsuna Sasaki

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Citations

Feb 1, 2011·Seminars in Arthritis and Rheumatism·Roberto Perez-AlvarezManuel Ramos-Casals

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