Ethanol endovascular management of brain arteriovenous malformations: initial results

Neurosurgery
Wayne F YakesE Prenger

Abstract

The goal was to determine the safety and efficacy of absolute ethyl alcohol treatment in the management of intra-axial brain arteriovenous malformations (AVMs). Seventeen patients (eight female and nine male patients; mean age, 41 yr) underwent ethanol endovascular therapy for treatment of their brain AVMs. Superselective amytal testing preceded all procedures. Neuroleptic intravenous anesthesia was used for 16 patients, and general anesthesia was used for 1 patient. Follow-up monitoring consisted of clinical evaluations, magnetic resonance imaging, and arteriography. In follow-up evaluations (mean follow-up period, 13 mo) after embolization of brain AVMs, neither vascular recanalization nor the neovascular recruitment phenomenon was observed in any patient. Progressive AVM thrombosis at arteriographic follow-up evaluation was a constant feature. Seven patients were cured of their AVMs with ethanol endovascular therapy alone. Three patients were cured of their lesions with ethanol embolization plus surgical resection. One patient was cured of his lesion with ethanol embolization and radiation therapy of the residual nidus. Three patients underwent only partial therapy, with significant improvement in symptoms. Three patients ar...Continue Reading

References

Jan 1, 1978·Clinical Neurosurgery·R F SpetzlerD Telles
Nov 1, 1990·Journal of Vascular and Interventional Radiology : JVIR·W F YakesJ Hodes
Sep 1, 1990·Radiographics : a Review Publication of the Radiological Society of North America, Inc·W F YakesT E Carter
Sep 1, 1989·Radiology·J M Eskridge
Mar 1, 1989·Radiology·W F YakesT E Carter
Nov 1, 1988·Radiology·D M WidlusA J Weiland
Mar 1, 1988·AJR. American Journal of Roentgenology·S TakebayashiK Matsui
Jul 1, 1987·Journal of Neurosurgery·R F SpetzlerE Wilkinson
Sep 1, 1987·Neurosurgery·B T Andrews, C B Wilson
Oct 1, 1986·Journal of Neurosurgery·R F Spetzler, N A Martin
Dec 1, 1981·Radiology·B A EllmanP C Peters
May 1, 1994·Radiographics : a Review Publication of the Radiological Society of North America, Inc·D M ColdwellW F Yakes
Feb 1, 1994·Neurosurgery·M G HamiltonG F Pineo
Feb 1, 1993·Journal of Neurosurgery·M K MorganN C Weber
Mar 1, 1996·Cardiovascular and Interventional Radiology·W F YakesH Odink
Mar 12, 1960·Journal of the American Medical Association·A J LUESSENHOP, W T SPENCE

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Citations

Oct 21, 2006·Neurosurgery·Michael J Alexander, Marshall E Tolbert
Jun 17, 2005·Cardiovascular and Interventional Radiology·Olivier JordanDaniel A Rüfenacht
Jul 12, 2005·Current Treatment Options in Cardiovascular Medicine·Franklin A Marden, Soma Sinha Roy
May 15, 2010·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·I M KesslerC Mounayer
Jul 16, 2014·Case Reports in Critical Care·Raya SabaNkemakolam Iroegbu
Jul 22, 2016·Journal of Neurointerventional Surgery·Matthew David AlexanderMatthew R Amans
Apr 29, 2005·Radiology·Young Soo DoIn-Wook Choo
May 22, 2009·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Kartik D BhatiaJason D Wenderoth
Jul 7, 2012·AJNR. American Journal of Neuroradiology·J PekkolaA Pitkäranta
Sep 30, 2000·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·M Al-YamanyM C Wallace
Jan 24, 2016·Journal of Neurointerventional Surgery·Jeremy J HeitUNKNOWN SNIS Standards and Guidelines committee
Feb 27, 2007·Stroke; a Journal of Cerebral Circulation·Italo Linfante, Ajay K Wakhloo
Nov 3, 2007·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Koniparambil P UnnikrishnanPuthuvassery R Suneel
Oct 31, 2007·Cardiovascular and Interventional Radiology·R GandiniG Simonetti
Mar 10, 2009·AJNR. American Journal of Neuroradiology·X D FanZ Y Zhang
Jan 23, 2015·A & a Case Reports·Kaori TachibanaShinichi Dozaki
Jul 21, 2009·AJNR. American Journal of Neuroradiology·L Z ZhengL X Su
Mar 30, 2004·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·J I HamadaY Ushio
Jul 19, 2006·The Orthopedic Clinics of North America·Gerald M Legiehn, Manraj K S Heran
Aug 19, 2008·Radiologic Clinics of North America·Gerald M Legiehn, Manraj K S Heran

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