Ethanol sclerotherapy or polidocanol sclerotherapy for symptomatic hepatic cysts

United European Gastroenterology Journal
Titus Fm WijnandsJoost Ph Drenth

Abstract

Over the past decades, multiple approaches to aspiration sclerotherapy of large symptomatic hepatic cysts have been investigated. However, comparative data are scarce. The objective of this article is to compare cyst reduction, symptomatic relief, and adverse events between ethanol sclerotherapy and polidocanol sclerotherapy. This retrospective study included adults having a symptomatic hepatic cyst treated at a European tertiary referral center with ethanol sclerotherapy (Center 1) or polidocanol-sclerotherapy (Center 2). We compared cyst diameter reduction (%) and symptom improvement (yes/no) within 12 months' post-treatment between centers using multivariate regression analyses adjusted for confounding factors. Finally, we compared adverse events using Fisher's exact test. We included 71 patients from Center 1 and 66 patients from Center 2 (median age 57 years; 126/137 (92%) female). Cyst reduction was comparable between Centers 1 and 2: 37.5% (IQR 15.7-61.0%) versus 44.2% (IQR 24.6-60.5%), respectively (p = 0.35). Correspondingly, symptomatic relief was comparable: 30/53 (56.6%) versus 43/66 (65.2%), respectively (p = 0.88). Center 1 reported significantly more (11 versus 3; p = 0.047) adverse events than Center 2. We found...Continue Reading

References

Nov 1, 1976·AJR. American Journal of Roentgenology·H M GoldsteinR S Nelson
Apr 1, 1989·The British Journal of Radiology·P A Gaines, M A Sampson
Feb 1, 1985·AJR. American Journal of Roentgenology·W J Bean, B A Rodan
Feb 1, 1994·Radiology·E vanSonnenbergP L Cooperberg
Mar 1, 1996·Journal of Vascular and Interventional Radiology : JVIR·T TikkakoskiM I Kairaluoma
Jul 31, 2003·Clinical Radiology·Z I Carrim, J T Murchison
Sep 21, 2006·AJR. American Journal of Roentgenology·Chien-Fang YangKwok-Hung Lai
Nov 26, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Joost P H DrenthVicente E Torres
Sep 12, 2012·The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology·Feng Yan-HongHu Xiangdong
Jan 9, 2013·Nature Reviews. Gastroenterology & Hepatology·Tom J G Gevers, Joost P H Drenth
Feb 26, 2014·Medical Ultrasonography·Zeno Spârchez, Pompilia Radu
Feb 9, 2016·Zeitschrift für Gastroenterologie·C F DietrichZ Sparchez
Mar 13, 2016·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Myrte K NeijenhuisJoost P H Drenth
Nov 9, 2016·AJR. American Journal of Roentgenology·Titus F M WijnandsJoost P H Drenth

❮ Previous
Next ❯

Citations

Sep 11, 2019·Liver International : Official Journal of the International Association for the Study of the Liver·Lucas H P BerntsEric T T L Tjwa

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Cardiovascular and Interventional Radiology
Chihiro ItouYutaka Imai
Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Casper JolinkErik van Spronsen
© 2022 Meta ULC. All rights reserved