Ethical considerations in global HIV phylogenetic research.

The Lancet. HIV
Cordelia E M ColtartEthics in HIV Phylogenetics Working Group

Abstract

Phylogenetic analysis of pathogens is an increasingly powerful way to reduce the spread of epidemics, including HIV. As a result, phylogenetic approaches are becoming embedded in public health and research programmes, as well as outbreak responses, presenting unique ethical, legal, and social issues that are not adequately addressed by existing bioethics literature. We formed a multidisciplinary working group to explore the ethical issues arising from the design of, conduct in, and use of results from HIV phylogenetic studies, and to propose recommendations to minimise the associated risks to both individuals and groups. We identified eight key ethical domains, within which we highlighted factors that make HIV phylogenetic research unique. In this Review, we endeavoured to provide a framework to assist researchers, public health practitioners, and funding institutions to ensure that HIV phylogenetic studies are designed, done, and disseminated in an ethical manner. Our conclusions also have broader relevance for pathogen phylogenetics.

Citations

Dec 28, 2018·The Journal of Infectious Diseases·Huldrych F Günthard, Roger Kouyos
Apr 5, 2019·Current Opinion in HIV and AIDS·Sanjay R MehtaSusan Little
Mar 19, 2019·Current Opinion in HIV and AIDS·Joel O WertheimArt F Y Poon
Apr 5, 2019·Current Opinion in HIV and AIDS·Lucie Abeler-DörnerUNKNOWN PANGEA consortium
Nov 26, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Guy Harling, Alexander C Tsai
May 15, 2020·Journal of the International AIDS Society·Brandon J Brown, Jeremy Sugarman
Jun 13, 2020·The Journal of Infectious Diseases·Hope R Lapointe, P Richard Harrigan
Jul 17, 2020·Journal of Clinical Microbiology·David BonsallUNKNOWN HPTN 071 (PopART) Team
Sep 17, 2020·Viruses·Ethan Romero-SeversonThomas Leitner
Sep 19, 2020·The American Journal of Bioethics : AJOB·Stephen Molldrem, Anthony K J Smith
Jan 11, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Yinfeng ZhangSusan H Eshleman
Aug 31, 2020·Wellcome Open Research·Stephanie Johnson, Michael Parker
Aug 28, 2020·Frontiers in Medicine·Abdul Rahman Jazieh, Zisis Kozlakidis
Sep 19, 2020·The American Journal of Bioethics : AJOB·Edwin J BernardSean Strub

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