Ethics in population-based genetic research

Accountability in Research
Matthew DeCamp, Jeremy Sugarman

Abstract

Population-based genetic research, including genetic epidemiology, shows tremendous potential to elucidate the role of genes as causal factors in complex and common human diseases. Like all research with human subjects, full realization of these benefits requires careful attention to its ethical conduct, establishing an appropriate balance between individual protections and the advancement of scientific and medical knowledge. This article reviews the growing literature on genetics research and ethics to describe some of the fundamental ethical issues in population-based genetics research, including research design, recruitment and informed consent, and dealing with research results. Its focus is on areas where consensus is forming and where future work is needed.

Citations

Sep 26, 2012·Trends in Molecular Medicine·Rebekah E McWhirterJohn R Condon
Jun 13, 2008·The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics·Ellen Wright Clayton
Jun 8, 2010·Science, Technology & Human Values·Robert Mitchell
Apr 9, 2005·Accountability in Research·Matthew DeCamp, Jeremy Sugarman
Jun 29, 2010·Current Protocols in Human Genetics·Jeffrey R Botkin
Apr 25, 2007·International Journal of Circumpolar Health·Bert B BoyerKathleen K McGlone
May 27, 2009·Current Opinion in Organ Transplantation·Nina M Schroder
Apr 23, 2008·Current Protocols in Human Genetics·Jeffrey R Botkin
Nov 18, 2020·Current Protocols in Human Genetics·Jeffrey R Botkin

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