Ethnic disparities in the association of impaired fasting glucose with the 10-year cumulative incidence of type 2 diabetes

Diabetes Research and Clinical Practice
W M AdmiraalI G M van Valkengoed

Abstract

Evidence of ethnic disparities in the conversion of prediabetes to type 2 diabetes is scarce. We studied the association of impaired fasting glucose (IFG) and fasting plasma glucose (FPG) with the 10-year cumulative incidence of type 2 diabetes in three ethnic groups. We analyzed data for 90 South-Asian Surinamese, 190 African-Surinamese, and 176 ethnic Dutch that were collected in the periods 2001-2003 and 2011-2012. We excluded those with type 2 diabetes or missing FPG data. We defined baseline IFG as FPG of 5.7-6.9 mmol/L. We defined type 2 diabetes at follow-up as FPG ≥ 7.0 mmol/L, HbA1c ≥ 48 mmol/mol (6.5%), or self-reported type 2 diabetes. 10-Year cumulative incidences of type 2 diabetes were: South-Asian Surinamese, 18.9%; African-Surinamese, 13.7%; ethnic Dutch, 4.5% (p<0.05). The adjusted association of baseline IFG and FPG with the 10-year cumulative incidence of type 2 diabetes was stronger for South-Asian Surinamese than for African-Surinamese and ethnic Dutch. The IFG (compared to normoglycaemia) ORs were 11.1 [3.0-40.8] for South-Asian Surinamese, 5.1 [2.0-13.3] for African-Surinamese, and 2.2 [0.5-10.1] for ethnic Dutch. The 10-year cumulative incidence of type 2 diabetes was higher and associations with baselin...Continue Reading

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Citations

Sep 1, 2015·The Canadian Journal of Cardiology·Eshan FernandoSonia S Anand
Jul 2, 2016·Diabetes Research and Clinical Practice·Chul-Hee KimJoong-Yeol Park
Oct 30, 2018·The Cochrane Database of Systematic Reviews·Bernd RichterYemisi Takwoingi
Jul 21, 2020·Annals of Human Biology·Sanne Pagh MøllerMette Frahm Olsen
Oct 7, 2017·American Journal of Hypertension·Frederieke S DiemerLizzy M Brewster
Feb 15, 2019·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Jeffrey I MechanickW Timothy Garvey
Feb 23, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Meghana D GadgilDavid M Herrington

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