Ethnic influence on nonalcoholic fatty liver disease prevalence and lack of disease awareness in the United States, 2011-2016

Journal of Internal Medicine
Michael H LeM H Nguyen

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a rising global disease associated with clinical and economic burdens. We aimed to quantify NAFLD prevalence and awareness to provide stakeholders necessary information to combat NAFLD burden. This study utilizes data from the National Health and Nutrition Examination Survey 2011-2016 and included 4538 adult participants who did not have heavy drinking or viral hepatitis history. The US fatty liver index defined NAFLD and NAFLD fibrosis score defined fibrosis. NAFLD awareness was captured by questionnaire. Amongst the study population of 4538 persons, NAFLD prevalence was 32.5%, lowest in non-Hispanic Blacks (18.0%) and Asians (18.1%), highest amongst Mexican Americans (48.4%). Within the NAFLD group, advanced fibrosis was highest in non-Hispanic Blacks (28.5%) and lowest amongst non-Hispanic Asians (2.7%). Of the 1473 (97.5%) NAFLD participants who answered NAFLD awareness question, 90% visited a healthcare centre at least once in the past year, but only 5.1% were aware of having NAFLD. On weighted population estimates, 77.33 million persons had NAFLD, 17.63 million had advanced fibrosis, and 73.39 million NAFLD participants were not aware of having NAFLD. Of 77.33 million people in ...Continue Reading

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Citations

Aug 17, 2020·Digestive Diseases and Sciences·Melissa MartinMindie H Nguyen
Dec 1, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Jie Li, Mindie H Nguyen
Jan 17, 2021·Liver International : Official Journal of the International Association for the Study of the Liver·Michelle ClaytonDina Attia
May 25, 2021·The Medical Journal of Australia·Stuart K RobertsWilliam W Kemp
May 26, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Vy H NguyenMindie H Nguyen
May 21, 2021·The Lancet. Gastroenterology & Hepatology·Nicole E RichAmit G Singal
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Jul 31, 2021·The American Journal of Gastroenterology·Jie LiMindie H Nguyen
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Sep 25, 2021·Hepatology Communications·Saleh A AlqahtaniZobair M Younossi
Oct 26, 2021·Journal of Gastroenterology and Hepatology·William KempStuart K Roberts

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