Ethnicity and mortality from systemic lupus erythematosus in the US.

Annals of the Rheumatic Diseases
E Krishnan, H B Hubert

Abstract

To study ethnic differences in mortality from systemic lupus erythematosus (lupus) in two large, population-based datasets. We analysed the national death data (1979-98) from the National Center for Health Statistics (Hyattsville, Maryland, USA) and hospitalisation data (1993-2002) from the Nationwide Inpatient Sample (NIS), the largest hospitalisation database in the US. The overall, unadjusted, lupus mortality in the National Center for Health Statistics data was 4.6 per million, whereas the proportion of in-hospital mortality from the NIS was 2.9%. African-Americans had disproportionately higher mortality risk than Caucasians (all-cause mortality relative risk adjusted for age = 1.24 (women), 1.36 (men); lupus mortality relative risk = 3.91 (women), 2.40 (men)). Excess risk was found among in-hospital deaths (odds ratio adjusted for age = 1.4 (women), 1.3 (men)). Lupus death rates increased overall from 1979 to 98 (p<0.001). The proportional increase was greatest among African-Americans. Among Caucasian men, death rates declined significantly (p<0.001), but rates did not change substantially for African-American men. The African-American:Caucasian mortality ratio rose with time among men, but there was little change among wo...Continue Reading

References

Nov 1, 1992·The American Journal of Medicine·M PetriM C Hochberg
Jan 1, 1990·Indian Journal of Pathology & Microbiology·N JayaramS Sehgal
Jun 1, 1981·Arthritis and Rheumatism·M F GordonR Schinnar
Apr 15, 1995·Annals of Internal Medicine·E J Huth
Jan 27, 1999·Arthritis and Rheumatism·K M UramotoS E Gabriel
May 8, 2000·Stroke; a Journal of Cerebral Circulation·O Fustinoni, J Biller
Oct 27, 2001·Lupus·G S Alarcón
May 23, 2002·MMWR. Morbidity and Mortality Weekly Report·UNKNOWN Centers for Disease Control and Prevention (CDC)
Sep 12, 2003·Current Rheumatology Reports·América G Uribe, Graciela S Alarcón

❮ Previous
Next ❯

Citations

Dec 2, 2006·Nature Reviews. Genetics·Peter K Gregersen, Timothy W Behrens
Aug 22, 2012·Social Work in Health Care·Carmen Ortiz Hendricks
Apr 3, 2009·Current Opinion in Rheumatology·Kristina L Demas, Karen H Costenbader
Sep 23, 2014·La Revue de médecine interne·L ArnaudZ Amoura
Oct 14, 2014·Autoimmunity Reviews·Jieyue LiaoQianjin Lu
Sep 4, 2014·Autoimmunity Reviews·Eyal ZimlichmanGisele Zandman-Goddard
Dec 17, 2014·Seminars in Roentgenology·Clinton JokerstSanjeev Bhalla
Dec 29, 2009·Autoimmunity Reviews·Andrea T BorchersM Eric Gershwin
Nov 11, 2008·Seminars in Arthritis and Rheumatism·Liang-Jing LuMichael H Weisman
Jun 24, 2008·Journal of the American Academy of Dermatology·Stéphanie Christen-ZaechAmy S Paller
Jul 19, 2014·Rheumatic Diseases Clinics of North America·Luis Alonso GonzálezGraciela S Alarcón
Jul 19, 2014·Rheumatic Diseases Clinics of North America·Judith A James
Feb 5, 2010·New Solutions : a Journal of Environmental and Occupational Health Policy : NS·Edith Marie WilliamsDavid Hahn-Baker
May 21, 2010·PloS One·Jeannie L TeJoshua O Ojwang
Nov 3, 2015·Seminars in Arthritis and Rheumatism·Yi-Chun MaJaung-Geng Lin
Nov 18, 2015·Seminars in Nephrology·Alberto J Sabucedo, Gabriel Contreras
Jun 19, 2013·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Carolina LlanosAlexis M Kalergis
Sep 3, 2013·Lancet·Fiona Goldblatt, Sean G O'Neill
Sep 18, 2012·Autoimmunity Reviews·Andrea T BorchersM Eric Gershwin
Jul 27, 2012·Revista clínica española·J Canora-LebratoA Zapatero-Gaviria
Feb 16, 2013·Journal of Autoimmunity·Sasha BernatskyAnn E Clarke
Sep 21, 2010·Autoimmunity Reviews·Paul P Smith, Caroline Gordon
May 6, 2008·American Journal of Obstetrics and Gynecology·Megan E B ClowseAndra H James
Jan 14, 2009·Translational Research : the Journal of Laboratory and Clinical Medicine·Elisa Y RhewRosalind Ramsey-Goldman
Oct 30, 2016·Revista clínica española·J CanoraUNKNOWN en representación de los investigadores del Registro RELES-Grupo de Enfermedades Autoinmunes Sistémicas (GEAS)
Sep 3, 2016·The Journal of Rheumatology·Jasvinder A SinghGeorge A Wells
Aug 26, 2016·Nature Reviews. Rheumatology·Erin E CarterAnn E Clarke
May 30, 2019·The New England Journal of Medicine·Sheila L ArvikarLena D Stuart

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.