PMID: 15226470Jul 1, 2004Paper

Ethnicity and race influence the folate status response to controlled folate intakes in young women

The Journal of Nutrition
Cydne A PerryM A Caudill

Abstract

Population-based studies report differences in folate status indicators among Mexican American (MA), African American (AA) and Caucasian (CA) women. It is unclear, however, whether these differences are due to variations in dietary folate intake. The present study was designed to investigate the influence of ethnicity/race on folate status parameters in MA, AA, and CA women (18-45 y; n = 14 in each group) under conditions of strictly controlled folate intake. In addition, the adequacy of the 1998 folate U.S. recommended dietary allowance (RDA), 400 micro g/d as dietary folate equivalents (DFE), for non-Caucasian women was assessed. Subjects (n = 42) with the methylenetetrahydrofolate reductase 677 CC genotype consumed a low-folate diet (135 micro g DFE/d) for 7 wk followed by repletion with 400 (7 MA, 7 AA, 7 CA) or 800 micro g DFE/d (7 MA, 7 AA, 7 CA) for 7 wk. AA women had lower (P </= 0.05) blood folate concentrations and excreted less (P </= 0.05) urinary folate throughout folate depletion and repletion with 400 and/or 800 micro g DFE/d compared with MA and/or CA women. MA women had lower (P </= 0.05) plasma total homocysteine (tHcy) throughout folate depletion and during repletion with 400 micro g DFE/d relative to the oth...Continue Reading

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Citations

Oct 31, 2006·BMC Cancer·Damali N MartinStefan Ambs
Aug 12, 2008·Journal of the American College of Nutrition·Jean HungMarie A Caudill
Aug 31, 2012·The American Journal of Clinical Nutrition·Allyson A WestMarie A Caudill
Mar 4, 2020·International Journal of Environmental Research and Public Health·Patrice JonesEmma Beckett
Jul 16, 2010·Expert Review of Molecular Diagnostics·Zsolt B NagyJózsef Gábor Joó
Aug 26, 2011·The Journal of Nutrition·Heather C HamnerMary Ann Johnson
Jul 23, 2013·Hemodialysis International·Saziye Sezin PalabiyikGönül Sahin
Jan 13, 2015·The Cochrane Database of Systematic Reviews·Amit D RavalRama Walia
Jul 18, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Muhammad AkramMahmood Akhtar Kayani
Mar 12, 2010·The American Journal of Clinical Nutrition·Marie A Caudill
Nov 21, 2020·Antioxidants·Kassidy BurgessNafisa M Jadavji

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