Ethological validation and the assessment of anxiety-like behaviours: methodological comparison of classical analyses and structural approaches

Behavioural Processes
François CalatayudA Aubert

Abstract

The research on emotional reactivity usually implies the use of standardised behavioural tests that provide a quick idea of the effect of a treatment on the reactivity of subjects to potentially dangerous situations. Many validity criteria have been considered to evaluate these tests. This validity concept supports the idea that animals' behaviour in these tests model human anxiety. Generally, those criteria repeatedly labelled as "ethological validation" refer to the analogy between animals and human in the meaning of the test situation. Although the content of the ethological validation concept is heterogeneous, it is steadily related to a fixed interpretation of the behavioural items produced in a given experimental setting. The basic assumption of such reasoning is that the behavioural items would always be expressed in the same behavioural context whatever the subject, its gender, strain or species, thoroughly asserting a predefined subjective state. Using multivariate and textual analysis, we found evidence that the "ethological validation" recourse to an a priori interpretation for a given behavioural variable may be deceptive. We defend the idea that the meaning of a behavioural variable should be restricted to the gene...Continue Reading

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Citations

Jan 5, 2013·Behavior Genetics·Timothy P O'LearyRichard E Brown
Aug 14, 2009·Epilepsia·Karine Yu SarkisovaGilles van Luijtelaar
Jun 10, 2014·Physiology & Behavior·A Ennaceur
Feb 13, 2016·Frontiers in Behavioral Neuroscience·Aron M Henriques-Alves, Claudio M Queiroz
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Aug 9, 2007·Brain Research Bulletin·A V KalueffP Tuohimaa
Feb 22, 2005·Brain Research. Brain Research Protocols·Allan V Kalueff, Pentti Tuohimaa
Jul 17, 2010·Brain Research·Neeraj Gilhotra, Dinesh Dhingra
Jan 31, 2006·Behavioural Processes·Allan V KalueffPentti Tuohimaa
Dec 17, 2005·Behavioural Brain Research·Bengt J MeyersonErika Roman
Aug 9, 2005·Neuroscience and Biobehavioral Reviews·A P Carobrez, L J Bertoglio
Aug 22, 2006·Behavioural Brain Research·A EnnaceurP L Chazot
Aug 10, 2016·Scientific Reports·Kevin S HollyTeresa A Murray
Mar 31, 2010·Criminal Behaviour and Mental Health : CBMH·Jacqui CampbellMary McMurran
Mar 14, 2019·International Journal of Language & Communication Disorders·Hilda SønsterudMargrethe Seeger Halvorsen
Jul 25, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Danqing XieWencui Wang

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