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Ethoxyformylation and guanidination of snake venom phospholipases A2: effects on enzymatic activity, lethality and some pharmacological properties

Toxicon : Official Journal of the International Society on Toxinology

Jan 1, 1983

E CondreaP Rosenberg

Abstract

Lysine residues in the basic and relatively toxic N. nigricollis phospholipase A2 and in the acidic and relatively nontoxic N. n. atra phospholipase A2 were modified by acylation with ethoxyformic anhydride (in the presence or absence of the substrate dihexanoyl lecithin) or guanidinati...read more

Mentioned in this Paper

Snake Venoms
Phospholipase A2, human
Naja naja atra
Enzymes, antithrombotic
Structure-Activity Relationship
Anticoagulant Activity
August Rats
Nonea atra
Lecithinum, lecithin, Homeopathic preparation
O-methylisourea
Paper Details
References
  • References22
  • Citations33
123
  • References22
  • Citations33
1234

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Ethoxyformylation and guanidination of snake venom phospholipases A2: effects on enzymatic activity, lethality and some pharmacological properties

Toxicon : Official Journal of the International Society on Toxinology

Jan 1, 1983

E CondreaP Rosenberg

PMID: 6857706

DOI: 10.1016/0041-0101(83)90005-3

Abstract

Lysine residues in the basic and relatively toxic N. nigricollis phospholipase A2 and in the acidic and relatively nontoxic N. n. atra phospholipase A2 were modified by acylation with ethoxyformic anhydride (in the presence or absence of the substrate dihexanoyl lecithin) or guanidinati...read more

Mentioned in this Paper

Snake Venoms
Phospholipase A2, human
Naja naja atra
Enzymes, antithrombotic
Structure-Activity Relationship
Anticoagulant Activity
August Rats
Nonea atra
Lecithinum, lecithin, Homeopathic preparation
O-methylisourea

Similar Papers Found In These Feeds

Cerebral Ventricle Neoplasms

Cerebral Ventricle Neoplasms are cancers that occur in the brain ventricles, which are structures that produce fluid for the spine and brain. Discover the latest research on Cerebral Ventricle Neoplasms here.

Related Papers

Paper Details
References
  • References22
  • Citations33
123
  • References22
  • Citations33
1234
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