PMID: 7327560Jan 1, 1981Paper

Etiological study of omphalocele

Human Genetics
A Czeizel, M Vitéz

Abstract

The epidemiological, teratological and genetic data on 134 index patients with omphalocele (79 isolated and 55 multiple ones) and on 134 matched controls born in Hungary 1970-1976 were studied medical records and by retrospective interview. The stillbirth rate and infant mortality are significantly higher, and there is intrauterine weight retardation and more frequent preterm delivery. The distribution of maternal age-groups shows a 'U-shaped' trend in isolated omphalocele. Spontaneous abortions were significantly higher, particularly in previous pregnancies of mothers of index patients. A striking higher incidence of early and late toxaemia was found in the pregnancies of mothers of the isolated omphalocele group. Sib occurrence was not found in 161 brothers and sisters. Thus amniotic fluid AFP examination is not recommended in subsequent pregnancies. The occurrence of other congenital abnormalities corresponds to 'random' risk.

References

Sep 1, 1979·Lancet·A Czeizel
Mar 1, 1976·Clinical Genetics·A Osuna, S Lindham
Feb 1, 1979·Archives of Disease in Childhood·S HavaladB D Speidel
Dec 1, 1977·American Journal of Diseases of Children·P M Colombani, M D Cunningham
Apr 1, 1972·The Journal of Urology·D S PetersenA S Cass
Dec 1, 1974·The Journal of Pediatrics·R D GreenwoodA S Nadas
Jan 1, 1971·Humangenetik·J Kucera, P Goetz
Jan 1, 1981·American Journal of Medical Genetics·A Czeizel
Jan 1, 1974·The Journal of Pediatrics·K L JonesM S Golbus
Jul 1, 1957·A.M.A. Archives of Surgery·R E ROTHENBERG

❮ Previous
Next ❯

Citations

Jul 29, 2009·Journal of Pediatric Surgery·T Mac BirdUNKNOWN National Birth Defects Prevention Study
Aug 8, 2015·Cadernos de saúde pública·Dilvania NicolettiLinjie Zhang
Nov 1, 1985·Prenatal Diagnosis·L B NielsenB Nørgaard-Pedersen
Nov 15, 1992·American Journal of Medical Genetics·P G PrydeM I Evans
Feb 1, 1984·American Journal of Medical Genetics·I W Lurie, H G Ilyina
Jun 1, 1984·Teratology·M L Martínez-FríasJ Zaplana
Nov 15, 1992·American Journal of Medical Genetics·P YangL Gordis
May 1, 1987·American Journal of Medical Genetics·H H ArdingerS Grant

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics
Peter Propping
European Journal of Epidemiology
J Ananijevic-PandeyD Brankovic
© 2022 Meta ULC. All rights reserved