Etiology and pediatric chronic kidney disease progression: Taiwan Pediatric Renal Collaborative Study

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Yuan-Yow ChiouHsin-Hsu Chou

Abstract

This study aims to examine the characteristics of Taiwanese children with chronic kidney disease (CKD) and delineate the factors that lead to disease progression in this population. We reviewed the records of the Taiwan Pediatric Renal Collaborative Study, a multicenter database of Taiwanese children with CKD. Multivariate regression analysis was used to identify the main factors associated with disease progression. A total of 382 children aged 1-18 years were included in the study (median age was 10.6 years; interquartile range: 6.4-13.8). There were 197 males (51.6%) and 185 females. CKD Stage 1 was diagnosed in 159 children (41.6%), Stage 2 in 160 (41.9%), Stage 3 in 51 (13.4%), and Stage 4 in 12 (3.1%). Fifty-six children (14.7%) experienced CKD progression. A multivariate analysis for all patients indicated that the risk for disease progression was increased in children with CKD secondary to a structural abnormality, genetic disease, anemia, elevated diastolic blood pressure, or elevated blood urea nitrogen. Compared with children with Stage 1 CKD, those with Stage 2 and Stage 4 CKD had decreased risk for CKD progression in this short-term cohort follow-up. CKD etiology affects disease progression. Careful monitoring and t...Continue Reading

References

Apr 3, 2003·Pediatrics·Gianluigi ArdissinoUNKNOWN ItalKid Project
Aug 3, 2004·Pediatrics·UNKNOWN National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents
May 9, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·UNKNOWN KDOQI, UNKNOWN National Kidney Foundation
Feb 21, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Bradley A Warady, Vimal Chadha
Mar 24, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Claudia González CeledónKjell Tullus
Jul 31, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Michel ChoncholLinda F Fried
Oct 18, 2007·Nature Clinical Practice. Nephrology·Ajay K Singh
Aug 30, 2008·Hypertension·Joseph T FlynnUNKNOWN Chronic Kidney Disease in Children Study Group
Dec 6, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Amy O StaplesLarry A Greenbaum
Jan 23, 2009·Journal of the American Society of Nephrology : JASN·George J SchwartzSusan L Furth
Oct 23, 2009·The New England Journal of Medicine·Elke WühlFranz Schaefer
Feb 12, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Tran Thi Mong HiepAnnie Robert
Jul 29, 2010·Nephron. Clinical Practice·Keng-Thye WooKok-Seng Wong
Sep 4, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Amy O StaplesCraig S Wong
Jun 30, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Jérôme HarambatE Jane Tizard
Apr 26, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Michiel F Schreuder
Oct 2, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Cynthia J WongSusan L Furth
Nov 9, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Oguz SoylemezogluGültekin Süleymanlar
Mar 8, 2013·Seminars in Nephrology·Katherine Wesseling-Perry, Isidro B Salusky
Apr 19, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Katarzyna Kiliś-PstrusińskaDanuta Zwolińska
Jan 18, 2014·Nephron. Clinical Practice·Akiko TodaMinoru Yamakado
Oct 1, 2012·Journal of Nephropathology·Jameela Kari

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.