PMID: 9635234Jun 23, 1998Paper

Etiology and risk factors of 180 cases of native valve endocarditis. Report from a 5-year national prospective survey in Slovak Republic

Diagnostic Microbiology and Infectious Disease
V HricakV Krcméry

Abstract

Risk factors, etiology, and outcome of 180 cases of infective endocarditis (IE) in the Slovak Republic for 5 years were prospectively studied in a national survey. According to the Duke Endocarditis Service Criteria (1994), 169 cases were considered definitive and 21 possible/probable. The aortic valve was infected in 46.7%, mitral in 47.2%, and tricuspidal/pulmonary in 6.1% of cases. The majority of endocarditis cases was caused by Staphylococcus aureus and coagulase-negative staphylococci (CNS) (33.3%); only 12.2% were due to viridans streptococci; 11.7% were due to Enterococcus faecalis; 6.1% due to Haemophilus spp.; 10.1% due to other organisms; and 26.7% were culture negative. Single positive cultures of CNS were not considered clinically significant. More than 25% of 180 patients were older than 60 years. Rheumatic fever was a risk factor in 35.5%, dental surgery in 20.5%, prior cardiosurgery in 7.8%, and neoplasia in 6.7%. All patients were treated with antimicrobials (average length of therapy was 29.5 days) and 33.3% of patients also had surgery (valvular prosthesis replacement). Forty (22.2%) died, and 140 (77.8%) survived at day 60 after the diagnosis of endocarditis was made. All 40 deaths were attributable to infec...Continue Reading

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Citations

Jul 10, 2003·Archives of Gerontology and Geriatrics·I Tomás CarmonaC Mella Pérez
May 24, 2011·Vascular Health and Risk Management·Stuart J HeadA Pieter Kappetein
Nov 30, 2011·Scandinavian Journal of Infectious Diseases·Olga DzupovaUNKNOWN Czech Infective Endocarditis Working Group
Jun 16, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R JurcoZ Pavlik
Apr 29, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R MicolC Larroche
Feb 2, 2006·European Journal of Epidemiology·Hakan LeblebiciogluSaban Esen

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