PMID: 9185124May 1, 1997Paper

Etiology of (CAG)n triplet repeat neurodegenerative diseases such as Huntington's disease is connected to stimulation of glutamate receptors

Medical Hypotheses
K M Fischer

Abstract

Chronic neurodegenerative diseases with expanded, genetically unstable (CAG)n triplet repeats include Huntington's disease. It is hypothesized that pathology results from excessive stimulation of glutamate receptors by glutamine.

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