Apr 27, 2000

Etiology of community-acquired pneumonia in 254 hospitalized children

The Pediatric Infectious Disease Journal
T JuvénO Ruuskanen

Abstract

Childhood community-acquired pneumonia is a common illness, but there have been relatively few comprehensive studies of the viral and bacterial etiology in developed countries. The aim of the present investigation was to determine the etiology of community-acquired pneumonia in hospitalized children by several laboratory methods. In a 3-year prospective study a nasopharyngeal aspirate for viral studies and acute and convalescent serum samples for viral and bacterial serology were taken from 254 children with symptoms of acute infection and infiltrates compatible with pneumonia in the chest radiograph. The role of 17 microbes was investigated. A potential causative agent was detected in 215 (85%) of the 254 patients. Sixty-two percent of the patients had viral infection, 53% had bacterial infection and 30% had evidence of concomitant viral-bacterial infection. Streptococcus pneumoniae (37%), respiratory syncytial virus (29%) and rhinovirus (24%) were the most common agents associated with community-acquired pneumonia. Only one patient had a positive blood culture (S. pneumoniae) of 125 cultured. A dual viral infection was detected in 35 patients, and a dual bacterial infection was detected in 19 patients. The possible causative ...Continue Reading

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References

Mentioned in this Paper

Respiratory Syncytial Virus Infections
Viral Studies
Mycoplasma pneumoniae
Virus Diseases
Plain X-ray
Hospitalization
Etiology
Anterior Thoracic Region
Infiltration
Study of Serum

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