Etiology of late cerebrovascular events after carotid endarterectomy.

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
F FluriS T Engelter

Abstract

Progressive carotid artery disease has been shown to cause cerebrovascular events years after a patient's carotid thromboendarterectomy (CEA). Yet, some late cerebrovascular events in CEA patients are attributable to other etiologies. We sought to determine frequency and characteristics of late cerebrovascular events in post-CEA patients attributable to etiologies other than progressive carotid disease. In a post hoc analysis of data from a CEA-registry with long-term follow-up, all patients with transient ischaemic attack (TIA) or stroke occurring >1 month post-CEA were identified. The etiologies of these events were dichotomized into the groups large-artery atherosclerosis (LAA) and that non-large-artery atherosclerosis (non-LAA), i.e. all other etiologies (Trial of Org 10172 in Acute Stroke Trial-criteria). Frequency and characteristics of both groups were compared. Sixty of 361 post-CEA patients (16.6%; 95%CI 12.9-20.9%) had late cerebrovascular events after 7 years (median). Thirty patients had ischaemic strokes and 30 had TIAs. These events were attributable to LAA in 48% (29/60) and to non-LAA in 52% (31/60). In the LAA group, contralateral carotid stenosis (62%; 18/29) was more frequent than recurrent ipsilateral stenos...Continue Reading

References

Jan 28, 1998·Stroke; a Journal of Cerebral Circulation·H FrericksJ H van Bockel
Sep 2, 1999·Stroke; a Journal of Cerebral Circulation·G G FergusonH J Barnett
Nov 2, 2002·Stroke; a Journal of Cerebral Circulation·E J CunninghamUNKNOWN European Carotid Surgery Trialists' Collaborative Group
Jan 14, 2004·Journal of Vascular Surgery·Kathleen G RamanSatish C Muluk
Aug 7, 2004·Journal of Vascular Surgery·Enzo BallottaClaudio Baracchini
Feb 16, 2006·Neurology·Bruce OvbiageleS Claiborne Johnston
May 15, 2008·Cerebrovascular Diseases·UNKNOWN European Stroke Organisation (ESO) Executive Committee, UNKNOWN ESO Writing Committee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.